In a nutshell In this study researchers compared conventional radiation therapy to hypofractionated radiotherapy. Some background Radiation therapy is a treatment used to kill cancer cells and is commonly used in the treatment of prostate cancer patients. Recent research suggests that increasing radiation doses above those used in conventional...
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In a nutshell This study assessed the survival rates and characteristics of metastatic colorectal cancer (CRC) patients with liver-limited disease (LLD) who underwent conversion chemotherapy. Some background Colorectal cancer patients may develop metastases (spread of the cancer to other distant organs and tissues of the body) and the liver is one...
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In a nutshell This review explored the risks and benefits of stereotactic body radiation therapy (SBRT) as treatment for patients with early-stage prostate cancer. Some background Prostate cancer (PC) can now be found in the very early stages, due to screening techniques such as the prostate-specific antigen or PSA (a protein produced by the...
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In a nutshell This study evaluated the safety and efficacy of chemotherapy (CT) given concurrently with 3-dimensional conformal radiotherapy (3D-CRT) for the treatment of patients with metastatic non-small cell lung cancer or mNSCLC (lung cancer that has spread to distant organs of the body). Some background Chemotherapy (CT) uses drugs that...
Read MoreIn a nutshell This review analyzed the available literature on the role, efficacy and safety of robotic surgery in comparison to laparoscopic surgery in patients with colorectal cancer. Some background Laparoscopic colorectal surgery (LCS) or “minimally invasive” surgery is a specialized technique for performing colorectal cancer...
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In a nutshell This study investigated the use of a sorafenib (Nexavar) for the treatment of non-small cell lung cancer. Some background Approximately 85% of lung cancers are classified as non-small cell lung cancers (NSCLC). NSCLC spreads easily throughout the lung tissue forming small malignant tumors. Although treatments have advanced in recent...
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In a nutshell This article reviewed the significance of the mTOR protein in breast cancer patients and its potential as a target for cancer treatments. Some background Current cancer treatments are often based on specific molecular activities of the cancer important for tumor growth and spread. For example, since the hormone estrogen...
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In a nutshell This trial assessed whether chemotherapy based on ERCC1 and RRM1 levels is more beneficial than the conventional carboplatin and gemcitabine (GemCarbo) chemotherapy, in patients with advanced non-small-cell-lung cancer (NSCLC). Some background ERCC1 and RRM1 are proteins found in human cells and are a part of the cell's cycle of...
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In a nutshell This review discusses current therapy as well as ongoing advances in the treatment of non small-cell lung cancer. Some background Many advances have been made in recent years in the treatment of non small-cell lung cancer (NSCLC). New technologies used in radiation therapy are allowing for a more targeted and precise delivery of...
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In a nutshell This study examined the predictors of survival in prostate cancer that has spread to the lymph nodes. Some background Prostate cancer (PC) is being diagnosed at earlier stages due to modern screening techniques, particularly the prostate-specific antigen (PSA) testing (an enzyme in the blood that is elevated in PC patients). Despite...
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In a nutshell This trial investigated the association between physical activity and the risk of recurrence (return of the cancer) and survival in patients with colon cancer (cancer of the large intestine). Some background The treatments of colon cancer have improved significantly over the years. However, many patients still have high risks for...
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In a nutshell This article reviewed the medical literature about the mTOR protein and the potential treatment of carcinoid tumors using mTOR inhibitors. Some background mTOR is a protein responsible for cell growth, proliferation and cell survival. A dysfunctional mTOR protein has been found in many types of cancer. Among these types...
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