In a nutshell The authors discussed isolated limb perfusion, a procedure used to deliver high doses of drugs straight to the site of the tumor in patients with melanoma. Some background Melanoma is sensitive to chemotherapy but it needs higher doses of chemotherapy than other types of cancer. Isolated limb perfusion is a complex...
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In a nutshell The authors examined whether eosinophils (white blood cells normally used to fight infections) levels in or around a colorectal tumor can help predict patient outcome. Some background Colorectal cancer is often classified using the tumor node metastasis system (TNM system). This system depends upon the assessment of primary...
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In a nutshell This study examined whether the protein HER3 is increased in colorectal tumors and in colorectal cancer liver metastases (cancer that has spread from the colon or rectum to the liver). Some background To improve colorectal cancer patients’ outcomes, anticancer treatments that target specific proteins are needed. High...
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In a nutshell The objective of this study was to determine if enzalutamide (Xtandi) is both safe and effective in patients with prostate cancer not previously treated with hormone therapy. Some background Androgen-deprivation therapy (ADT) is one of the main treatments for advanced prostate cancer. Many ADT drugs can lower levels of...
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In a nutshell The authors aimed to determine the effect of degarelix in treating prostate cancer. Some background Hormone therapy is a prostate cancer treatment that targets the male sex hormones active in prostate cancer, such as testosterone. Degarelix (Firmagon) is a drug used in hormone therapy that reduces the levels of testosterone to...
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In a nutshell The objective of this paper was to determine how skin cancer patients with tumor thickness of > 4mm could benefit from a diagnostic procedure known as sentinel lymph node biopsy. Some background Melanoma is a type of cancer that starts in color-producing cells of the skin. It can grow deep into the inner layers of skin...
Read MoreIn a nutshell The authors aimed to determine long-term survival in advanced skin cancer patients treated with ipilimumab. Some background Advanced melanoma is skin cancer that has spread deep within the skin to other sites of the body. There are limited treatments available for advanced skin cancer and patients have poor five-year survival...
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In a nutshell This paper compared primary and secondary breast cancers in adolescents and young adults. Some background Primary breast cancer refers to the first cancer that starts growing from the breast. Secondary breast cancer refers to breast cancer on the other breast that did not occur at the same time as the inital cancer, breast cancer...
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In a nutshell This study investigated whether the levels of certain cancer markers (CEC and soluble CD146) could predict the outcome for patients with non small cell lung cancer (NSCLC) undergoing surgery. Some background Markers for a disease are generally proteins which are detected at high levels in one group of patients. These markers can be...
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In a nutshell The authors aimed to determine the psychological effect of advanced lung cancer on patients and their family caregivers. Some background Patients with advanced lung cancer experience higher levels of emotional and physical distress compared to patients with other cancers, which can effect their own suffering as well as their...
Read MoreIn a nutshell The authors aimed to determine the effect of cytokine-induced killer cells for treatment of non-small cell lung cancer. Some background Cytokine-induced killer cells (CIK) are man-made immune cells (fight infection and disease) that can recognize infected or cancerous cells in the absence of other immune cells, which allows for...
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In a nutshell The authors aimed to identify emerging and current hormone treatments available for prostate cancer. Some background Male hormones are active in healthy cell growth and play a large role in cancer development in patients with prostate cancer by aiding cancer cell growth. Hormone therapy targets the male sex hormones produced during...
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