In a nutshell The current study explored the association between sun exposure and melanoma outcome. Some background Physicians normally advise against excessive sun exposure due to the increased risk of skin cancer. However, recent studies have suggested that sun exposure may be associated with lower mortality rates among melanoma patients. The...
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In a nutshell This review investigated treatment options following biochemical recurrence after primary treatment for prostate cancer. Some background Prostate cancer can be treated using a variety of methods, the most common being partial or full removal of the prostate gland, a procedure known as a prostatectomy. Other treatments include...
Read MoreIn a nutshell This study evaluated whether the lymph node ratio (LNR) is an accurate predictor of breast cancer prognosis, and whether LNR can identify which patients would benefit from post-mastectomy radiation therapy (PMRT). Some background Breast cancer staging allows physicians to estimate prognosis, and helps guide treatment planning. Under...
Read MoreIn a nutshell This article compares breast conserving therapy and mastectomy as primary treatments for breast cancer in young patients. Some background In young patients with localized (confined) breast cancer, surgical treatment which leaves as much breast tissue as possible is often preferred. This type of surgery is called breast...
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In a nutshell This study examined whether fatty liver disease protects colorectal cancer patients from developing liver metastasis. Some background Colorectal cancer (CRC) is most likely to metastasize (spread) to the liver. Liver metastasis accounts for 50% of all cases of metastatic colorectal cancer. Since very limited treatments are...
Read MoreIn a nutshell This study examined whether tamoxifen (nolvadex) can reduce the risk of contralateral breast cancer in women diagnosed with breast cancer and the BRCA1 or BRCA2 genetic mutation. Some background The BRCA1 and BRCA2 genetic mutations are associated with a high risk of developing breast cancer. While prophylactic mastectomies (a...
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In a nutshell This study evaluated survival rates after a local recurrence (return of the cancer close to the place of the initial cancer) in young breast cancer patients treated with breast conserving surgery. Some background Young patients with early stage breast cancer are usually treated with breast conserving surgery or BCS (removal of the...
Read MoreIn a nutshell In this study, researchers examined two methods of delivering radiation therapy as a treatment for breast cancer. They compared the cosmetic outcomes of breasts treated with targeted intraoperative radiotherapy (TARGIT) or external beam radiotherapy (EBRT). Some background Medical and technological improvements have enhanced survival...
Read MoreIn a nutshell This study examines the efficacy of a type of radiotherapy called accelerated partial breast irradiation (APBI) as an adjuvant (additional) treatment for breast cancer patients who underwent lumpectomy. Some background Patients with early-stage breast cancer are usually treated with breast conserving surgery or lumpectomy (surgery...
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In a nutshell This article looked at the pathological features of prostate cancer to identify those patients who would benefit the most from adjuvant radiotherapy after radical prostatectomy. Some background One option for patients with prostate cancer is surgery to remove the cancer along with the entire prostate gland and some healthy tissues...
Read MoreIn a nutshell In this study researchers examined the effect of a specific chemotherapy combination on disease-free survival in patients with node negative breast cancer. FAC treatment was compared to FAC treatment plus paclitaxel (FACwP). Some background A combination of the drugs fluorouracil (efudex), doxorubicin (doxil), and cyclophosphamide...
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In a nutshell This study looked at men who had their prostate removed after diagnosis of prostate cancer. The study evaluated the time from surgery to biochemical recurrence, and whether this period of time is associated with survival or certain cancer characteristics. Some background One of the initial treatments for prostate cancer is a radical...
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