In a nutshell This article looked at the influence of calpain-9 on breast cancer survival following endocrine therapy. Some background Calpain-9 is a protein that is important in the processes of cell signalling (communication between cells). Irregular expression of these proteins can be seen in breast cancer and some of these proteins can even...
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In a nutshell This paper studied whether a mindfulness meditation program could reduce stress and depression in young breast cancer survivors. Some background Studies have shown that younger women are more stressed and depressed compared to older women after being diagnosed with cancer. They are also more likely to be fatigued and have sleep...
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In a nutshell The aim of this trial will be to determine whether participating in a physical activity program, along with health education, is more effective at decreasing colorectal cancer recurrence than health education alone. The primary outcome measured in this trial will be disease-free survival (how long following treatment a patient remains...
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In a nutshell This article reviewed the current views on how best to monitor colorectal cancer survivors in order to detect return of cancer locally or at new sites as early as possible. Some background Over 1 million individuals develop colorectal cancer each year and 66% of these patients will be treated surgically with curative intent....
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In a nutshell This study examines the 15-year cancer-specific and overall survival in men treated with prostate brachytherapy. Some background Brachytherapy is a form of radiotherapy used for the treatment of some cancers including prostate cancer. It involves a radiation source being implanted inside the...
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In a nutshell This article looked at the potential benefits of following a structured exercise program after lung cancer surgery. Some background Lung cancer surgery often involves removing a part of the lung in order to remove the entire tumor. Patients undergoing such operations often have poor exercise tolerance and lung function after the...
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In a nutshell This study examined whether the timing of adjuvant chemotherapy affects survival among women with breast cancer. Some background Surgical resection to remove all cancerous tissue is the standard of care for the treatment of breast cancer. After surgery, many patients also undergo adjuvant treatments (additional therapy following...
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In a nutshell This review explored the most appropriate surveillance methods for detecting and reducing mortality associated with recurrences (return of the cancer) of colorectal cancer. Some background Due to treatment advances and lowering death rates, there are increasing numbers of colorectal cancer survivors. Therefore, appropriate...
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In a nutshell This study investigated which traits of low-risk breast cancer can predict the risk of cancer recurrence after treatments. Some background The majority of women who are diagnosed with breast cancer have node-negative cancer, meaning breast cancer that has not spread to regional lymph nodes. Node-negative breast cancer patients have a...
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In a nutshell This study evaluated the use of EndoPredict in predicting late metastatic recurrence in ER+ breast cancer patients. Some background Hormonal treatment of estrogen receptor positive (ER+) breast cancer is routinely continued for 5 years following diagnosis. However, over 50% of all cancer recurrences, and over 66% of cancer related...
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In a nutshell This study examined the effectiveness of routine surveillance imaging in detecting melanoma recurrence and increasing life expectancy. Some background Melanoma survivors are routinely examined for evidence of cancer recurrence since early detection of recurrence significantly improves survival. Although the importance of recurrence...
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In a nutshell This study examined the use of low-intensity and high-intensity surveillance schedules in the follow-up of breast cancer survivors. Some background The number of women diagnosed with breast cancer rises every year. However, breast cancer treatments have also improved dramatically in recent decades, and mortality rates are...
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