In a nutshell This study evaluated the risk of cardiovascular disease mortality among long-term survivors of classical Hodgkin lymphoma (cHL). The data showed that patients with early-stage HL are at a higher risk of mortality from cardiovascular disease than from cancer. Some background cHL is a cancer that starts in white blood cells called...
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Fertility preservation for young people with blood cancer
In a nutshell This review looked at options to preserve future fertility for young people diagnosed with blood cancer. Some background For teens and young adults, blood and bone marrow cancers are one of the most common types of cancer. These include Hodgkin lymphoma (HL), non-Hodgkin lymphoma (NHL), and acute myeloid leukemia. Fortunately, blood...
Read MoreIs long-term treatment-free remission possible after frontline nilotinib treatment in patients with chronic phase chronic myeloid leukemia?
In a nutshell This study provided an updated 5-year assessment of treatment-free remission (TFR) after frontline nilotinib (Tasigna) treatment in patients with chronic-phase (CP) chronic myeloid leukemia (CML). The data showed sustained, long-term high TFR rates with effectiveness and safety in these patients. Some background Long-term treatments...
Read MoreNon-drug therapies for the management of menopausal symptoms in breast cancer survivors.
In a nutshell This article looked at different types of non-drug therapies for the management of menopausal symptoms (MS) such as night sweats and hot flushes in breast cancer (BC) survivors. The authors concluded that cognitive-behavioral therapy (CBT) and hypnosis may offer some benefit for these women. Some background BC is the most common cancer...
Read MoreEvaluating treatment-free remission in patients with chronic myeloid leukemia
In a nutshell This study aimed to investigate treatment-free remission in patients with chronic myeloid leukemia. This study concluded that some patients can experience late relapses and that long term follow-up is mandatory for these patients. Some background Treatment-free remission (TFR) can be used in patients with chronic myeloid...
Read MoreCan biological therapies nivolumab and ipilimumab prevent stage IV melanoma from returning?
In a nutshell This study examined if biological therapies nivolumab (Opdivo) and ipilimumab (Yervoy) could safely prevent cancer return in patients with stage IV melanoma that has been surgically removed. The results showed that nivolumab and ipilimumab were effective at preventing recurrence but nivolumab alone was safer for patients. Some...
Read MoreThe effects of continued blinatumomab therapy in adult patients with relapsed/refractory acute lymphoblastic leukemia
In a nutshell The study evaluated treatment outcomes in patients with relapsed/refractory (R/R) acute lymphoblastic leukemia (ALL) who continued blinatumomab (Blincyto; BL) after initial therapy. The authors found that long-term BL therapy can improve survival in these patients. Some background 45% of adults with ALL experience R/R...
Read MoreEvaluating the risk of late relapse in patients with acute lymphoblastic leukemia
In a nutshell This study aimed to investigate the occurrence and characteristics of late relapse in adult patients with acute lymphoblastic leukemia. This study concluded that late relapse in these patients is not uncommon and leads to better outcomes after relapse compared to early relapse. Some background Late relapse is the return...
Read MoreSurviving cancer – is there a greater risk of cardiovascular disease long-term?
In a nutshell This study investigated if there is a higher risk of cardiovascular disease (CVD) in cancer survivors. They found that cancer survivors have a higher risk of CVD. Some background Improved cancer detection and treatment has increased the rates of survival. The number of cancer survivors living for more than 10 years is growing. Some...
Read MoreSurviving cancer – is there a greater risk of cardiovascular disease long-term?
In a nutshell This study investigated if there is a higher risk of cardiovascular disease (CVD) in cancer survivors. They found that cancer survivors have a higher risk of CVD. Some background Improved cancer detection and treatment has increased the rates of survival. The number of cancer survivors living for more than 10 years is growing. Some...
Read MoreOncological safety of testosterone replacement therapy in prostate cancer survivors after definitive local therapy
In a nutshell This study aimed to evaluate the use of testosterone replacement therapy (TRT) in men who had definitive treatment for prostate cancer. The authors concluded that TRT was not associated with a higher risk of recurrence in these patients. Some background Prostate cancer (PCa) is commonly fueled by the sex hormone testosterone....
Read MoreSearching for patients with breast cancer to test an anti-fatigue treatment.
In a nutshell This phase 3 trial will investigate the effect of bupropion (Wellbutrin) to treat fatigue in patients with breast cancer (BC). The main outcomes will be fatigue, quality of life and depression. This trial is recruiting across the United States. The details After treatment for breast cancer (BC), many women report feeling...
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