In a nutshell This study evaluated the safety and effectiveness of the herpes zoster vaccine (Shingrix) in patients with blood cancer who are receiving anti-cancer therapy. This study concluded that the Shingrix vaccine was effective in these patients, with manageable side effects. Some background Shingles is caused by a virus called herpes zoster....
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In a nutshell This study aimed to investigate outcomes for patients with chronic-phase chronic myeloid leukemia who received nilotinib as a first-line treatment. This study concluded that nilotinib is a valuable treatment option for these patients. Some background Nilotinib (Tasigna) is a targeted therapy...
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In a nutshell This study aimed to investigate treatment response and outcome for patients of 75 years and older with chronic myeloid leukemia treated with imatinib (Gleevec). This study concluded that imatinib is important in the frontline treatment of these patients. Some background...
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In a nutshell This study aimed to investigate if a modified Berlin-Frankfurt-Münster (BFM) regimen would be a safe and effective method of treatment for adult patients with newly diagnosed acute lymphoblastic leukemia (ALL). This study concluded that this regimen is well tolerated and effective...
Read MoreIn a nutshell This study aimed to investigate the relationship between immunoglobulin (Ig) levels and clinical outcomes in patients with chronic lymphocytic leukemia. This study concluded that levels of IgG and IgA at diagnosis are important prognostic markers for infection in these patients. Some background Immunoglobulins (Ig)...
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In a nutshell This study aimed to investigate the ending of imatinib treatment in patients with chronic-phase chronic myeloid leukemia who had at least 2 years of deep molecular response from imatinib first line treatment. This study concluded that the duration of treatment and residual...
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In a nutshell This trial is investigating the effectiveness of adding chemotherapy drug venetoclax to a standard chemotherapy treatment for patients with acute myelogenous leukemia (AML). The main outcome for this study would be the maximum amount of the drug that gives the most benefits to patients and the effectiveness of the drug. This study...
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In a nutshell This study investigated female fertility preservation (FFP) in cancer patients. They found that FFP should be discussed with all women of reproductive age undergoing cancer treatment. Some background Cancer can have many negative effects on patient health. Infertility is a particular concern for younger female patients. Pregnancy rates...
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In a nutshell This study aimed to compare the effectiveness of an adult treatment regimen and a pediatric-inspired regimen in adult patients with acute lymphocytic leukemia. This study concluded that the pediatric-inspired regimen is superior to the adult treatment regimen for these patients. Some background Many...
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In a nutshell This study compared the safety and effectiveness of blinatumomab (Blincyto) with chemotherapy in the treatment of acute lymphoblastic leukemia (ALL). Researchers found the survival was higher with blinatumomab than chemotherapy alone. Some background Patients with unresponsive or relapsed ALL treated with chemotherapy have...
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In a nutshell This study is evaluating how well CPI-613 plus chemotherapy works in older patients with acute myeloid leukemia (AML) that has come back or stopped responding to treatment. The main outcome to be measured will be the number of patients who have a complete disappearance of all signs of cancer. This trial is taking place across the United...
Read MoreIn a nutshell This study aimed to compare levels of early complete remission in patients with acute myeloid leukemia (AML) treated with standard or sequential high-dose chemotherapy. This study concluded that sequential high-dose chemotherapy led to early complete remission in these patients. Some background Sequential high-dose...
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