In a nutshell This study examined treatment outcomes in patients with chronic myeloid leukemia (CML) treated with second-line tyrosine kinase inhibitors (TKIs). Researchers concluded that treatment responses with second-line TKIs are stable over time. Patients with less favorable treatment outcomes can be identified early during therapy. Some...
Read MoreCurrent disease status-First occurrence of the leukemia Posts on Medivizor
Ibrutinib versus ofatumumab: Immunotherapy versus targeted therapy for relapsed or persistent CLL
In a nutshell This study compared the effectiveness of ibrutinib (Imbruvica) and ofatumumab (Arzerra) in treating relapsed or persistent chronic lymphocytic leukemia (CLL). Researchers concluded that ibrutinib improved survival and disease progression more than ofatumumab. Some background Chemotherapy and immunotherapy are usually the first-line...
Read MoreCan donor stem cell transplants improve CLL in poor-risk patients?
In a nutshell This study looked at the safety and effectiveness of donor stem cell transplantation in chronic lymphocytic leukemia (CLL) patients who have not responded well to previous treatments. The authors concluded that stem cell transplants can lead to long-term minimal residual disease-free survival for up to one-half of patients. Some...
Read MoreNewer treatment options for CLL
In a nutshell This study reviewed the current treatment options for chronic lymphocytic leukemia. Some background Chronic lymphocytic leukemia (CLL) is a common form of leukemia in Western countries. Treatment options for CLL depend on the stage of the disease (the severity) and the overall health and fitness of the patient. Patients with...
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