In a nutshell This guideline reviewed treatment options for patients with newly diagnosed uveal melanoma. Some background The uvea is the middle layer of the eye. It is made up of the iris (the colored part of the eye), the ciliary body (a muscle in the eye), and the choroid (a layer of tissue in the back of the eye). In uveal melanoma (UM), tumors...
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In a nutshell This paper is a document that was developed at a breast cancer conference by a number of experts in the field. It outlines suggested treatment for early-stage breast cancer. The experts concluded that patients and doctors should work together and discuss the benefit of treating early-stage breast cancer in comparison with the potential...
Read MoreIn a nutshell This study wanted to find out if surgically removing the main tumor in breast cancer which has spread throughout the body would impact the survival of the patient. The study found that removing the primary tumor resulted in a longer overall survival in patients with breast cancer that has spread. Some background A common treatment for...
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In a nutshell This study investigated the effectiveness of pelvic radiotherapy (PRT) followed by chemotherapy and surgery in advanced rectal cancer. Researchers suggested that this combined treatment is associated with improved survival rates. Some background Rectal cancer affects 44,180 people each year in the US. Up to 80% of these people present...
Read MoreIn a nutshell This study investigated preimplantation genetic testing for aneuploidy (PGT-A) for fertility preservation (FP). They found that PGT-A was useful in cancer patients attempting FP. Some background Assisted reproductive technology (ART) is used to treat infertility. It is also an important option for cancer patients. Cancer...
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In a nutshell This study compared the safety and effectiveness of short-term androgen deprivation therapy (ADT) combined with radiotherapy (RT) in patients who underwent radical prostatectomy (RP). The main finding was that the combination of ADT and RT reduced the risk of recurrence and disease progression in these patients. Some background RP is...
Read MoreIn a nutshell This trial is examining the effectiveness of ultra-high-dose hypofractionated or single-dose radiotherapy for intermediate (medium) risk prostate cancer. The main outcome that will be measured will be the number of patients that experience side effects. This study is being conducted in New York City, NY, the US. The details...
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In a nutshell This study investigated the outcomes of radical prostatectomy (RP) without pelvic lymph node dissection (PLND) in patients with prostate cancer. The main finding was that 5 years after treatment, 100% of patients at low risk for cancer recurrence had survived. Some background PLND is surgery to remove the lymph nodes from the pelvis....
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In a nutshell This study wanted to see how well the medication afatinib (Giotrif) works in real-life settings, outside of clinical trials in patients with advanced non-small cell lung cancer (NSCLC). The study found that patients treated with afatinib had a good response rate and survival. Some background There are many...
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In a nutshell This study investigated the effectiveness of panitumumab (Vectibix) in the treatment of advanced colorectal cancer (CRC). Researchers suggested that this drug improved tumor response to the therapy. Some background CRC is one of the most common cancer worldwide. Chemotherapy such as FOLFOXIRI (leucovorin, fluorouracil, oxaliplatin,...
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In a nutshell This study compared the effectiveness of chemotherapy combined with bevacizumab (Avastin) or anti-EGFR drugs for treating advanced colorectal cancer (CRC). Researchers suggested that anti-EGFR later introduced in the treatment of these patients did not impact the outcomes of patients. Some background CRC is the third most common...
Read MoreIn a nutshell This study compared hormone therapy and chemotherapy for the treatment of metastatic (cancer that has spread) breast cancer. The authors concluded that hormone therapy plus targeted therapy is better than chemotherapy for patients with metastatic breast cancer. Some background Different types of breast cancer have different receptors....
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