In a nutshell The authors assessed the safety and efficacy of ramucirumab (Cyramza) for patients with metastatic colorectal cancer (cancer that has spread from the colon or rectum to distant sites) that has progressed despite treatment. Some background Ramucirumab has recently been approved for the treatment of metastatic colorectal cancer....
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In a nutshell The authors examined whether chemotherapy can benefit metastatic colorectal cancer patients (patients whose cancer has spread from the colon or rectum to distant sites) with high ECOG scores. Some background The ECOG scoring system measures how much the cancer is impacting a patient’s daily living abilities (performance...
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In a nutshell The authors aimed to evaluate if the outcomes of surgery following chemotherapy are different based on the focality of breast cancer tumors. Some background Breast cancer can be characterised as 'unifocal', 'multifocal and 'multicentric'. This refers to the number of areas in which the cancer can be found...
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In a nutshell The authors aimed to determine the effect of degarelix in treating prostate cancer. Some background Hormone therapy is a prostate cancer treatment that targets the male sex hormones active in prostate cancer, such as testosterone. Degarelix (Firmagon) is a drug used in hormone therapy that reduces the levels of testosterone to...
Read MoreIn a nutshell This study examined cancer relapse rates and treatment options for patients with colorectal lung metastases (colorectal cancer that has spread to the lungs) after curative lung surgery. Some background Roughly 20% of patients with colorectal cancer will have cancer in a distant organ by the time they are diagnosed. The cancer will...
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In a nutshell The authors aimed to determine whether age had an effect on patient quality of life after localized prostate cancer treatment. Some background Localized prostate cancer is cancer that is confined within the prostate gland. Treatment for localized prostate cancer can cause undesirable effects in patients, affecting their quality...
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In a nutshell This study examined the safety and efficacy of bevacizumab (Avastin) for treating elderly patients with metastatic colorectal cancer (cancer that has spread from the colon or rectum to distant sites). Some background Bevacizumab is an anti-cancer drug that blocks the formation of new blood vessels needed for the cancer to grow and...
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In a nutshell The aim of this research was to analyze the effect of a diagnostic procedure known as sentinel lymph node biopsy on survival in patients with head and neck skin cancer. Some background Melanoma is a type of cancer that starts in color-producing cells of the skin. It can grow deep into the inner layers of skin and spread into...
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In a nutshell This paper studied the effect of lapatinib (Tyverb) plus capecitabine (Xeloda) versus trastuzumab (Herceptin) plus capecitabine in patients with human epidermal growth factor receptor 2 (HER2) positive breast cancer that has spread to other parts of the body. Some background Trastuzumab is used to treat HER2 positive breast...
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In a nutshell This study aimed to evaluate the complications associated with robotic-assisted prostate removal (minimally invasive) compared to an open surgical procedure (more invasive). Some background Open surgical removal of the prostate has previously been the traditional surgical approach for prostate cancer treatment. Robot-assisted...
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In a nutshell This study aimed to assess use of dacomitinib in patients with advanced non-small cell lung cancer (NSCLC) who had previously failed to respond to chemotherapy and erlotinib (Tarceva). Some background NSCLC is the most common type of lung cancer. Erlotinib and gefitinib (Iressa) are used to treat NSCLC. They...
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In a nutshell This study is being carried out in New York and New Jersey. It will examine whether adding panitumumab (Vectibix) to chemotherapy reduces the risk of the cancer returning in colorectal cancer patients with liver metastases (cancer that has spread to the liver). The authors will also record any adverse events experienced and patient...
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