In a nutshell The authors evaluated the effect of dabrafenib (Tafinlar) in disease progression in melanoma patients with cancer that has spread to the brain (metastasis). Some background In advanced melanoma (stage III/IV) cancer spreads from the skin to other parts of the body, most commonly, to the brain. In...
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In a nutshell The authors determined the effect of hormone therapy for the treatment of localized prostate cancer. Some background Localized prostate cancer is confined within the prostate gland. Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones active in prostate cancer,...
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In a nutshell The authors assessed the effect of depression on men with newly diagnosed prostate cancer. Some background Localized prostate cancer is confined within the prostate gland. Common treatments in prostate cancers include prostate surgery, hormone therapy and radiation therapy. Prostate surgery involves surgically...
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In a nutshell The authors compared the effectiveness of robot-assisted and open prostate surgery in prostate cancer patients. Some background Prostate surgery is a common treatment option in prostate cancer. It involves surgically removing the prostate gland. There are numerous types of prostate surgery. Open radical prostate...
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In a nutshell The authors aimed to determine whether testing circulating tumor cells for the presence of human epidermal growth factor receptor 2 (HER2) could aid in determining treatment options. Some background Circulating tumor cells (CTC’s) are cells from a primary tumor that have migrated into the blood stream. Their presence is...
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In a nutshell The authors compared scar satisfaction in prostate cancer patients who underwent different surgical procedures. Some background Surgical removal of prostate gland is a common treatment in prostate cancer. There can be different types of surgical techniques. Laparascopic surgery (standard surgery) involves several small...
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In a nutshell The authors determined the association between perineural invasion (cancer on the nerves inside the prostate) and disease progression in men with prostate cancer on active surveillance (watchful waiting). Some background Active surveillance is common in early stage (stage I or II) prostate cancer. It involves actively...
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In a nutshell The authors analyzed the effectiveness of standard melanoma treatments in the management of acral melanoma (a type of skin cancer affecting specific parts of a body). Some background Acral melanoma affects the skin of the limbs, ears, fingers or nails. The occurrence of acral melanoma is most common in people with darker...
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In a nutshell The authors determined how positive surgical margins increased the risk of prostate cancer return in patients following prostate surgery. Some background Prostate surgery is a common treatment in prostate cancer that involves surgically removing the prostate gland. Surgical margin refers to the visible normal tissue...
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In a nutshell The authors evaluated melanoma patients with liver metastasis (spread of cancer from the skin to liver) undergoing surgery or other treatments. Some background In advanced melanoma (stage IV), cancer often spreads from the skin to the liver. There are two treatment options in liver metastasis – surgery and...
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In a nutshell This study examined whether levels of microRNA-21 could predict the patient response to chemo-radiotherapy delivered before they had surgery. Some background Almost a third of colorectal cancer is rectal cancer. The treatment for this cancer which has started to spread is a combination of chemotherapy,...
Read MoreIn a nutshell This phase III trial aims to determine the effects of hypo-fractionated radiation compared to standard radiation therapy. The main outcome to be investigated is whether hypo-fractionated radiation has similar or better results when compared to standard radiation. This trial is recruiting in in Illinois, Oklahoma and Virginia, in the...
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