In a nutshell This study summarized updated guidelines for risk assessment and appropriate management approaches for prostate cancer. Some background Treatment options for prostate cancer require careful assignment of patients to risk groups. The tumor stage (extant of disease) is determined by rectal examinations and imaging results. A...
Read More
In a nutshell This study examined the impact of different breast cancer subtypes in elderly patients. The study concluded that HER2+ disease had the highest rate of metastatic spread in elderly breast cancer patients. Some background Breast cancer is classified into different subtypes depending on the presence or absence of certain receptors....
Read More
In a nutshell This study examined the safety and effectiveness of androgen deprivation therapy (ADT) plus docetaxel (Taxotere) compared to ADT alone for metastatic prostate cancer. Researchers reported increased progression-free survival and overall survival when ADT was combined with docetaxel. Some background ADT is a type of hormone therapy...
Read More
In a nutshell This trial aimed to assess the effectiveness of using erlotinib (Tarceva) to treat EGFR-mutation positive advanced non-small-cell lung cancer. The study concluded that erlotinib had an overall survival (OS) benefit comparable to first line chemotherapy. Some background Genetic mutations (changes) in the epidermal growth factor...
Read MoreIn a nutshell This study compared the safety and effectiveness of two forms of imaging-guided radiation techniques for prostate cancer. Researchers reported more favorable outcomes with intensity modulated radiation therapy (IMRT) than with 3-dimensional conformal radiation therapy (3DCRT). Some background Radiation therapy is a common treatment...
Read More
In a nutshell The authors determined the benefits and pitfalls of active surveillance (AS). The authors concluded that AS may reduce over-treatment in low-risk prostate cancer patients without compromising 10-year prostate cancer survival. Some background AS is a form of non-treatment used in prostate cancer patients who are low-risk. This...
Read MoreIn a nutshell This phase 3 trial aims to evaluate the benefit of a diet and exercise program in overweight men with low-risk prostate cancer. The main outcome to be investigated is a change in blood sugar metabolism in prostate cancer cells. The trial is recruiting in Seattle (Washington), USA. The details Low-risk prostate cancer is often managed...
Read More
In a nutshell This study investigated the safety and effectiveness of the drug eribulin (Halaven) for the treatment of patients with metastatic breast cancer and resistance to taxane therapies. The study concluded that eribulin was effective and well tolerated in patients with metastatic breast cancer. Some background Taxanes are a type of...
Read More
In a nutshell This study investigated the association between the tumor side and cetuximab (Erbitux) effectiveness in metastatic (spread to other parts of the body) colorectal cancer. Researchers reported that cetuximab was more effective in left-sided tumors. Some background Left and right- sided colorectal cancer have different...
Read More
In a nutshell This study examined the predictive value of circulating tumor cells (CTCs) during docetaxel (Taxotere) treatment for metastatic castration-resistant prostate cancer (mCRPC). Researchers reported a strong association between CTCs and treatment response to docetaxel. Some background Hormone therapy is the standard of care for advanced...
Read MoreIn a nutshell This review examined recent findings and recommendations for the management of low-risk localized prostate cancer. Authors concluded that watchful waiting and active surveillance are suitable options for most men with low-risk prostate cancer. Some background Due to advances in the early detection of prostate cancer, many prostate...
Read More
In a nutshell This study investigated the predictors of recovery of patients with colorectal cancer two years after surgery. Researchers reported that depression and capacity to manage problems before surgery are associated with health and well-being in recovery two years after surgery. Some background The support a cancer patients receives...
Read More
