In a nutshell This study examined the safety and effectiveness of radium-223, alone or in combination with other therapies, in treating metastatic castration-resistant prostate cancer (mCRPC). Researchers concluded that radium-223 was well tolerated and can be safely combined with additional therapies. Combined therapies were associated with improved...
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In a nutshell This study examined prostate surgery as a treatment option for older prostate cancer patients compared to younger patients. The authors concluded that prostate cancer patients aged 75 years or more can be suitable candidates for surgery. Some background Radical treatment options for prostate cancer, such as surgery, are often not...
Read MoreHow do I manage my side effects for better quality of life? Patient Power founder and host, Andrew Schorr, facilitates a dialogue between advanced prostate cancer experts, Dr. William Catalona, Dr. Russell Szmulewitz of University of Chicago Medical Center, and Judith Paice, PhD, RN to discuss managing and communicating treatment side effects. ...
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In a nutshell This study looked at the benefit of additional hormone therapy in premenopausal women with hormone receptor-positive HER2 negative (HR+ HER2-) early breast cancer. They found that patients at higher risk of cancer returning showed greatest benefit from exemestane (Aromasin) plus ovarian function suppression (OFS). Some background HR+...
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In a nutshell This study investigated whether the neutrophil count (NC; a type of white blood cell) and neutrophil-to-lymphocyte (another type of white blood cell) ratio (NLR) can predict prognosis in metastatic (spread to other parts of the body) melanoma patients treated with ipilimumab (Yervoy). Researchers suggested that the NC and NLR are...
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In a nutshell This study examined the evidence for combining androgen deprivation therapy (ADT) with radiation therapy for the treatment of high-risk localized prostate cancer. Authors concluded that the combined therapy approach was associated with a survival advantage for intermediate- and high-risk patients. Some background ADT is a type...
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In a nutshell This study looked at the effect of adding bevacizumab (Avastin) to letrozole (Femara) treatment in patients with hormone receptor-positive (HR+) metastatic (spread to other areas) breast cancer. They found that bevacizumab treatment prolonged the amount of time before patients experienced worsening of their...
Read MoreIn a nutshell This study compared external beam radiation therapy (EBRT) and hypofractioned EBRT (H-EBRT) for low-risk localized prostate cancer. Researchers reported no differences in disease progression or survival. However, an increase in side effects was observed with H-EBRT. Some background Radiation therapy is a common treatment for...
Read MoreIn a nutshell This study investigated the efficiency of endoscopic methods for tumor removal in early colorectal cancers when compared to surgery. Researchers reported that surgery is associated with higher curative rates when compared to endoscopic tumor removal. Some background Surgical removal of the tumor is the standard treatment for...
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In a nutshell The main objective of this trial is to determine patient response to eribulin (Halaven) followed by doxorubicin (Adriamycin) and cyclophosphamide (Cytoxan) treatment. The main outcome to be measured is number of patients who experience a complete response to treatment (disappearance of signs of cancer). This trial is being conducted...
Read MoreIn a nutshell This study evaluated recommendations for the management of prostate cancer in older men. Authors concluded that older men should be managed according to their individual health status and cancer risk classification, rather than by age. Some background The ageing of the population is expected to increase the number of older men living...
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In a nutshell This study investigated the optimal waiting time between radiation therapy and surgery in rectal cancer patients. Researchers suggested that a prolonged waiting time is associated with tumor shrinkage. Some background Surgery is the only curative treatment for rectal cancer. Chemotherapy and radiation therapy is the recommended...
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