In a nutshell The authors aimed to determine the benefit of exercise before and after prostate cancer diagnosis and its effect on prostate cancer-specific mortality in men. The authors concluded that men with non-metastatic (cancer that has not spread into surrounding organs) prostate cancer who exercised more after diagnosis had a lower risk of...
Read MoreCurrent disease status-First occurrence of the cancer Posts on Medivizor
Hypofractionated compared to conventional radiation in prostate cancer patients
In a nutshell The authors aimed to determine the efficacy and safety of hypofractionated radiation therapy compared to conventional radiation therapy in men with localised prostate cancer. The authors concluded that hypofractionated therapy was beneficial to men with localised prostate cancer, without enhancing side effects, in comparison to...
Read MoreIs targeted chemotherapy for stage II/III rectal cancer before surgery effective?
In a nutshell This study examined the effect of pre-surgical chemotherapy without radiotherapy in stage II/III rectal cancer. The study showed that combined targeted chemotherapy was effective in these patients. Some background Rectal cancer is a cancer of the end part of the digestive system. In stage II and III, the cancer has begun to...
Read MoreRecommendations for second-line therapy in men with hormone-resistant prostate cancer
In a nutshell This review outlined the opinions of the American Society of Clinical Oncology for the treatment of hormone therapy resistant men with prostate cancer. Some background Advanced prostate cancer is cancer that has spread outside the prostate gland into surrounding organs. In some cases, cancer can become hormone-resistant. This is when...
Read MoreAbiraterone plus prednisone therapy in men with advanced prostate cancer
In a nutshell The authors aimed to determine the benefit of abiraterone acetate (Zytiga) plus prednisone (Deltasone) with hormone therapy in men with newly diagnosed, advanced prostate cancer. The authors concluded that adding abiraterone acetate plus prednisone to hormone therapy significantly increased overall survival and progression-free survival...
Read MoreLooking at immunotherapy for late stage non-small-cell lung cancer
In a nutshell This trial looked at the effectiveness of the immunotherapy nivolumab (Opdivo) for patients with advanced non-small-cell lung cancer (NSCLC). The authors concluded that nivolumab resulted in similar survival rates compared to chemotherapy. They did however state that it was safer in terms of side effects. Some background Chemotherapy...
Read MoreThe effect of apalutamide on advanced, hormone-resistant prostate cancer
In a nutshell The authors aimed to determine the effectiveness of apalutamide before or after treatment with abiraterone acetate (Zytiga) and prednisone (Deltasone) in men with advanced, hormone-resistant prostate cancer. The authors concluded that apalutamide was a safe treatment option and demonstrated effectiveness against advanced,...
Read MoreLooking for participants with metastatic colorectal cancer to undergo treatment with targeted therapy
In a nutshell The aim of this phase 2 trial is to compare the effectiveness of the combined treatment with chemotherapy, avelumab (Bavencio) and the vaccine Ad-CEA in patients with metastatic (spread to other parts of the body) colorectal cancer. The main outcome to be measured is tumor response to the treatment. This trial will recruit in Maryland,...
Read MoreLocal therapy and improved survival in advanced prostate cancer
In a nutshell The authors aimed to compare outcomes after local therapy versus no local therapy in men with advanced prostate cancer (cancer that has spread outside the prostate gland). The authors concluded that local therapy resulted in better outcomes when compared to no local therapy. They also concluded that in patients who received local...
Read MoreLooking for patients to compare high and low dose brachytherapy
In a nutshell The aim of this trial was to determine the difference in quality of life on urination when treated with low dose rate (LDR) and high dose rate (HDR) brachytherapy. This study is being conducted in Kelowna, British Columbia, Canada. The details Brachytherapy is a form of radiation therapy that places radioactive material either within...
Read MoreIs active surveillance suitable for prostate cancer patients regardless of age?
In a nutshell This study aimed to investigate the relationship between patient age and active surveillance outcomes in prostate cancer (PC). This study concluded that younger patients undergoing AS were less likely to see an increased Gleason score and progression. Some background Early stage PC that has not yet spread is often not treated...
Read MoreProteins in the prostate gland can help predict disease recurrence after surgery
In a nutshell This study examined if the collections of proteins in the prostate can predict prostate surgery outcomes. Authors found that protein analysis was a significant predictor of disease recurrence and metastasis (cancer spread) after surgery. Some background Prostate surgery is a first-line treatment option for prostate cancer. It has...
Read More
