In a nutshell This study aimed to investigate the effectiveness of cabazitaxel used for patients with metastatic castration-resistant prostate cancer. This study found that patients treated with cabazitaxel had maintained or improved quality of life and pain control. Some background One treatment option for prostate cancer is androgen deprivation...
Read MoreIn a nutshell This trial is examining the effectiveness of chemotherapy and atezolizumab (Tecentriq), given before surgery, for triple negative breast cancer. The main outcomes to be measured will be response in the breast tissue and lymph nodes and survival. The details Triple negative breast cancer is not dependent on the HER2 receptors or...
Read MoreIn a nutshell This study aimed to investigate the best timing of treatment verification imaging used in radiation therapy for patients with prostate cancer. This study found that patients undergoing daily imaging had less risk of their cancer returning and had reduced rectal side-effects. Some background One main treatment option for prostate cancer...
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In a nutshell This study aimed to evaluate the use of abiraterone (Zytiga) and olaparib (Lynparza) in advanced prostate cancer. This study concluded that olaparib in combination with abiraterone provided clinical benefit for patients with metastatic castration-resistant prostate cancer compared with abiraterone alone. Some background...
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In a nutshell This study aimed to discover the optimal timing of hormone therapies in combination with androgen-deprivation therapy (ADT) for patients with metastatic hormone-sensitive prostate cancer. This study found that treatment with a second hormone therapy after prostate cancer becomes immune to hormone treatment is associated...
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In a nutshell This study aimed to evaluate short and medium-term patient-reported side-effects after robotic prostate surgery. This study found that patient-reported outcome measures evaluating urinary symptoms and health related quality of life do not significantly change after robotic prostate surgery. Some background...
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In a nutshell This study looked at a combination of chemotherapy and an antiangiogenic drug bevacizumab to treat patients with advanced non-small-cell lung cancer. The authors concluded that this combination may have potential to control cancer in these patients. Some background Despite the major advances in cancer treatments in recent years,...
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In a nutshell This study looked at the effectiveness and safety of a combination of two cancer drugs, everolimus (Afinitor) and exemestane (Aromasin), in women after menopause with advanced breast cancer. The authors found that these drugs were safe and effective in the treatment of these women. Some background Breast cancer is...
Read MoreIn a nutshell This trial examined the effectiveness of combining the targeted therapy drug pembrolizumab (Keytruda) with chemotherapy at treating certain types of advanced non-small-cell lung cancer. The trial concluded that this combination is more beneficial than chemotherapy alone for treating this subset of patients. Some background PD-1...
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In a nutshell This study investigated the effectiveness of a 3-month oxaliplatin-based chemotherapy treatment after surgery in patients with stage 3 colon cancer. Researchers suggested 6-months of treatment is associated with better outcomes. Some background The current standard treatment for stage 3 colon cancer patients is surgery followed by...
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In a nutshell This study examined the survival rates of melanoma patients with brain metastasis treated with new therapies. Researchers concluded that PD-1 agents are associated with improved survival outcomes. Some background More than 50% of melanoma patients develop brain metastasis (cancer spread), with an overall survival of 17 to 22 weeks....
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In a nutshell This study examined the effectiveness of encorafenib (Braftovi) alone or in combination with binimetinib or vemurafenib (Zelboraf) alone in BRAF-mutant melanomas. Researchers suggested that the combined treatment showed improved cancer outcomes with manageable side effects. Some background Some melanoma patients have a...
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