In a nutshell This study aimed to evaluate two less invasive surgeries in the treatment of localized prostate cancer (PCa). This study found that there was no difference in urinary symptoms 12 months after the two methods. Some background Prostate surgery is a treatment option for prostate cancer (PCa). This surgery can be carried out by classic...
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In a nutshell This study aimed to investigate the link between PSA (prostate-specific antigen) levels and prostate cancer (PCa) prognosis. This study found that a lower PSA level (less than 0.2ng/ml) was associated with less risk of dying from PCa. Some background The PSA is a substance produced by the prostate. It can be used as a marker during...
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In a nutshell This article investigated the long-term safety and effectiveness of autologous breast reconstruction (ABR; uses tissue from another place on your body to form a breast shape) on women after breast removal for invasive breast cancer. The authors concluded that this treatment is safe and had no effect on relapse...
Read MoreIn a nutshell This trial aims to see if combining two medications, pembrolizumab (Keytruda) and RO7198457 (a new experimental vaccine) is better than just using pembrolizumab in treating advanced melanoma that has not been treated before. The main outcome that will be measured is how long the patients go without cancer growing. The study is being...
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In a nutshell This study evaluates the effectiveness of an immunotherapy in the treatment of newly diagnosed prostate cancer. The main outcome to be measured in this trial is the number of patients whose cancer does not progress within 3 years after immunotherapy injection. This trial is taking place in many sites across the USA. The details...
Read MoreIn a nutshell This study aimed to investigate the outcomes of active surveillance (AS) in the treatment of localized prostate cancer. This study recommends the use of AS for men with localized prostate cancer. Some background Treatments for prostate cancer often result in serious side effects such as impaired bowel, bladder or sexual functions....
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In a nutshell This article investigated the safety and effectiveness of epacadostat and pembrolizumab (Keytruda) for patients with advanced melanoma. The authors concluded that this therapy is safe and has encouraging effectiveness in these patients. Some background The immune system normally works to detect...
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In a nutshell This trial is comparing drug therapy and drug therapy with prostate surgery or radiation for the treatment of advanced prostate cancer. The main outcome to be measured is overall survival. This trial is recruiting in Houston (Texas), USA. The details Prostate cancer can be treated by medication, surgery or...
Read MoreIn a nutshell This trial aims to test the safety and effectiveness of adding a new drug called NKTR-214 to treatment with nivolumab (Opdivo) is better than just using nivolumab alone. The main outcomes that will be measured are how many people respond to treatment, how long the patients go without cancer growing or spreading, and overall...
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In a nutshell This study examined how safe and effective is biosimilar ABP 215 in non-small cell lung cancer (NSCLC), compared to bevacizumab (Avastin). This study concluded that this drug is as safe and effective as bevacizumab in these patients. Some background Non-small cell lung cancer (NSCLC) is the most common type of lung...
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In a nutshell This article investigated the long-term safety and effectiveness of oncoplastic breast surgery (removal of the tumor and breast reconstruction at the same time) on women survivors of breast cancer. The authors concluded that this treatment is safe and resulted in acceptable long-term outcomes. Some background Breast conservative...
Read MoreIn a nutshell This study compared robotic and laparoscopic complete mesocolic surgery (CMS) in patients with colon cancer. Researchers suggested that both surgeries were safe and associated with excellent outcomes. Some background Colorectal cancer is the third most common cancer in the US. After the standard treatment, 30 to 40% of the patients...
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