In a nutshell This trial looked at the use of short-course radiotherapy (RT) followed by chemotherapy (CT) and delayed surgery to reduce distant metastases (tumor spread) in patients with locally advanced rectal cancer (LARC). The trial found that this treatment was more effective in controlling distant metastases when compared to standard...
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In a nutshell This study compared the surgical outcomes of patients undergoing single-port extraperitoneal prostatectomy (SP-EPP) with conventional multiport transperitoneal robot-assisted radical prostatectomy (MP-RARP). The data showed that the SP-EPP approach was associated with a shorter length of hospital stay as well as a reduction in pain...
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In a nutshell This study evaluated the benefits of chemotherapy after surgery in patients with T1bN0M0 triple-negative breast cancer (TNBC). The data showed that chemotherapy after surgery resulted in similar outcomes as patients who did not undergo chemotherapy. Some background Triple-negative breast cancer (TNBC) is a subtype of breast...
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In a nutshell The study examined whether delaying prostate surgery affected the outcomes of patients with high-risk localized prostate cancer. The authors found that the procedure could be safely delayed in these patients for up to 6 months after initial diagnosis without higher risks of adverse outcomes. Some background Radical prostatectomy...
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In a nutshell This study compared the effects of intensity-modulated radiation therapy (IMRT) with a simultaneously integrated boost (SIB) to conventional radiotherapy (CRT) with a sequential boost (SeqB) following breast-conserving surgery (BCS) in patients with breast cancer. The data showed that both radiotherapy techniques...
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In a nutshell This study investigated the effectiveness and safety of pembrolizumab (Keytruda) plus chemotherapy in patients with inoperable or metastatic triple-negative breast cancer. The data showed that the combination is effective in improving progression-free survival in these patients. Some background Triple-negative breast cancer (TNBC)...
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In a nutshell This study was carried out to assess the long-term outcomes of men diagnosed with prostate cancer (PC) undergoing active surveillance (AS) and factors that predicted the risk of their cancer spreading (metastasizing). The authors found that AS is a safe and viable option for men with low-risk and carefully-selected intermediate-risk...
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In a nutshell This study looked at the outcomes of older women with triple-negative breast cancer who received chemotherapy before or after local treatment. The data showed that chemotherapy can be considered in the treatment of these patients. Some background Triple-negative breast cancer (TNBC) is a subtype of breast cancer (BC) that tests...
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In a nutshell The study compared outcomes of lorlatinib (Lorbrena) with crizotinib (Xalkori) in patients with previously untreated advanced non-small-cell lung cancer (NSCLC) with ALK mutations (genetic abnormalities). The main finding was that patients receiving lorlatinib had longer progression-free survival (PFS) and a higher response in the...
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In a nutshell This study aimed to investigate the outcomes of accelerated partial breast irradiation (ABPI) with TomoTherapy (TT) after breast conservative surgery (BCS) in patients with invasive breast cancer. This study concluded that this treatment is safe and effective with good long-term outcomes in these patients. Some...
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In a nutshell This study was carried out to assess the long-term safety and effectiveness of magnetic resonance imaging (MRI)-guided transurethral ultrasound ablation (TULSA) in patients with localized prostate cancer. The authors found that TULSA was safe and effective, with preserved quality of life. Some background Prostate cancer is one...
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In a nutshell This study investigated the effectiveness of treatment with irinotecan (Camptosar) combined with capecitabine (Xeloda) chemotherapy (ICC) before rectal cancer surgery. Researchers suggested that this combined therapy significantly improved the treatment outcomes in these patients. Some background Rectal cancer is a common...
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