In a nutshell This study compared the safety and effectiveness of short-term androgen deprivation therapy (ADT) combined with radiotherapy (RT) in patients who underwent radical prostatectomy (RP). The main finding was that the combination of ADT and RT reduced the risk of recurrence and disease progression in these patients. Some background RP is...
Read MoreCurrent disease status-First occurrence of the cancer Posts on Medivizor
Searching for patients to try a radiation treatment strategy for prostate cancer.
In a nutshell This trial is examining the effectiveness of ultra-high-dose hypofractionated or single-dose radiotherapy for intermediate (medium) risk prostate cancer. The main outcome that will be measured will be the number of patients that experience side effects. This study is being conducted in New York City, NY, the US. The details...
Read MoreWhat are the effects of radical prostatectomy without pelvic lymph node dissection in prostate cancer?
In a nutshell This study investigated the outcomes of radical prostatectomy (RP) without pelvic lymph node dissection (PLND) in patients with prostate cancer. The main finding was that 5 years after treatment, 100% of patients at low risk for cancer recurrence had survived. Some background PLND is surgery to remove the lymph nodes from the pelvis....
Read MoreAfatinib as first-line treatment for advanced EGFR-mutant non-small cell lung cancer
In a nutshell This study wanted to see how well the medication afatinib (Giotrif) works in real-life settings, outside of clinical trials in patients with advanced non-small cell lung cancer (NSCLC). The study found that patients treated with afatinib had a good response rate and survival. Some background There are many...
Read MorePanitumumab improves the treatment outcomes of patients with advanced colorectal cancer
In a nutshell This study investigated the effectiveness of panitumumab (Vectibix) in the treatment of advanced colorectal cancer (CRC). Researchers suggested that this drug improved tumor response to the therapy. Some background CRC is one of the most common cancer worldwide. Chemotherapy such as FOLFOXIRI (leucovorin, fluorouracil, oxaliplatin,...
Read MoreA later introduction of anti-EGFR drug is as effective as the standard therapy for advanced colorectal cancer
In a nutshell This study compared the effectiveness of chemotherapy combined with bevacizumab (Avastin) or anti-EGFR drugs for treating advanced colorectal cancer (CRC). Researchers suggested that anti-EGFR later introduced in the treatment of these patients did not impact the outcomes of patients. Some background CRC is the third most common...
Read MoreComparing endocrine treatment versus chemotherapy for metastatic breast cancer
In a nutshell This study compared hormone therapy and chemotherapy for the treatment of metastatic (cancer that has spread) breast cancer. The authors concluded that hormone therapy plus targeted therapy is better than chemotherapy for patients with metastatic breast cancer. Some background Different types of breast cancer have different receptors....
Read MoreEvaluating long-term outcomes of nivolumab plus ipilimumab for patients with advanced melanoma
In a nutshell This study compared nivolumab (Opdivo) plus ipilimumab (Yervoy) to either drug alone for the treatment of advanced melanoma. The authors concluded that nivolumab plus ipilimumab or nivolumab alone increased survival compared to ipilimumab alone for these patients. Some background Advanced melanoma is a type of skin cancer that...
Read MoreSurgery followed by chemotherapy improves the outcomes of patients with rectal cancer
In a nutshell This study investigated the effectiveness of surgery followed by chemotherapy without chemoradiotherapy (CRT) before surgery to treat rectal cancer. Researchers suggested that this treatment improves the outcomes of these patients. Some background Colorectal cancer is the third most common cancer worldwide. The standard...
Read MoreFocal high-intensity focussed ultrasound for the treatment of localized prostate cancer
In a nutshell This study aimed to evaluate the use of high-intensity focal ultrasound (HIFU) for the treatment of localized prostate cancer. This study found that HIFU is a safe treatment with good oncological results and minimal side-effects. Some background High-intensity focused ultrasound (HIFU) is a non-invasive technique that uses...
Read MoreTotal testosterone density as a marker of tumor load in patients with prostate cancer
In a nutshell This study aimed to investigate a new way to evaluate prostate cancer risk, through the total testosterone density (TTD). This study found that TTD can be used to help manage patients with low-risk PCa. Some background Testosterone is a hormone that is made by the testicles. It usually fuels the growth of...
Read MoreLooking for patients with prostate cancer to test a combination of radiotherapy
In a nutshell This phase 2 trial will investigate the effectiveness of stereotactic ablative radiation therapy (SABR) and radiopharmaceutical therapy (RPT) in patients with oligometastatic (cancer spread in 1-2 other tissues or organs) prostate cancer. The main outcome will be progression-free survival (PFS). This trial is recruiting in Maryland,...
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