In a nutshell This study evaluated the effectiveness and safety of trastuzumab deruxtecan (Enhertu) in patients with previously untreated metastatic HER2-mutant non-small-cell lung cancer (NSCLC). The data showed that trastuzumab deruxtecan was safe and showed strong anticancer activity in these patients. Some background NSCLC is the most common form...
Read More
In a nutshell This study evaluated short-course radiation therapy (RT) followed by chemotherapy as a non-surgical treatment of patients with rectal cancer (RC). The data showed that treatment with short-course RT and chemotherapy is safe and effective for these patients. Some background Colorectal cancer (CRC) is one of the most common types of...
Read More
In a nutshell This study compared the effectiveness and safety of S-1 (tegafur/gimeracil/oteracil) and oxaliplatin (Eloxatin) combined with bevacizumab (Avastin) or with cetuximab (Erbitux) in patients with previously untreated advanced colorectal cancer with wild-type KRAS. This study concluded that the safety and effectiveness of...
Read More
In a nutshell This study assessed whether robot-assisted radical prostatectomy (RARP) improves lower urinary tract symptoms (LUTS) and quality of life (QoL) in patients with prostate cancer (PCa). The data showed an improvement in LUTS and QoL in patients with previously moderate or severe LUTS, 12 months after RARP. Some background PCa...
Read More
In a nutshell This study compared the effectiveness and safety outcomes of platinum-based chemotherapy and immune checkpoint inhibitors (ICIs) for the treatment of patients with early-stage triple-negative breast cancer (TNBC). The data showed that ICI plus chemotherapy was associated with good outcomes with reduced side effects compared with...
Read More
In a nutshell This study looked at the use of robotic-assisted CyberKnife radiosurgery to treat iris melanomas. It found that this is a promising treatment for iris melanoma. Some background Melanomas are the most common tumors of the eye. Eye melanomas usually occur at the back of the eye, but sometimes they affect the iris (the colored...
Read More
In a nutshell This study investigated the frequency and outcomes of contralateral axillary metastasis (CAM) in patients with inflammatory breast cancer (IBC). The data showed that CAM was common at diagnosis in patients with IBC and was best identified by ultrasound and positron emission tomography (PET). Some background IBC is a rare and aggressive...
Read More
In a nutshell This study evaluated the rates of local, regional, and distant recurrence between patients who received immediate or delayed autologous deep inferior epigastric perforators (DIEP) flap breast reconstruction (BR). The data showed that there is an increased risk for breast cancer (BC) recurrence in women who received a delayed BR...
Read More
In a nutshell This study examined the use of paclitaxel (Taxol) and carboplatin (Paraplatin) as weekly chemotherapy (CT) with trastuzumab (Herceptin) and pertuzumab (Perjeta) in HER2+ breast cancer (BC) in order to reduce toxicity rates. The authors found that the weekly regimen of chemotherapy can be considered an alternative to standard chemotherapy...
Read More
In a nutshell This study looked at whether age is related to a risk of poor outcomes in men undergoing delayed radical prostatectomy (RP; prostate removal surgery) following active surveillance (AS). The authors found that older patients require closer monitoring when on AS and may require additional testing to identify the progression of their...
Read More
In a nutshell This study was carried out to assess the use of aromatase inhibitors (AI) versus tamoxifen (Novaldex) for women before menopause with estrogen receptor-positive (ER+) breast cancer (BC). The authors found that AIs were associated with better outcomes than tamoxifen in these patients. Some background About 80% of all BCs...
Read More
In a nutshell The study aimed to compare the effectiveness of surgery versus radiation therapy for patients with high-grade localized prostate cancer (PCa). The study concluded that surgery was associated with improved survival compared to radiation therapy in these patients. Some background Prostate cancer (PCa) is the second most common...
Read More
