In a nutshell This study aimed to determine the long-term outcomes and risk factors after allogeneic stem cell transplantation (allo-SCT) for patients with advanced phase chronic myeloid leukemia (CML). This study concluded that allo-SCT improved the outcomes of these patients, particularly in those with donors younger than 36...
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In a nutshell This study aimed to investigate if the combination of dasatinib and decitabine was safe and effective in patients with advanced chronic myeloid leukemia. This study concluded that this treatment is safe and effective in these patients. Some background Treatment of advanced-phase chronic myeloid...
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In a nutshell This study investigated the interactions between tyrosine kinase inhibitors and other drugs taken at the same time in patients with chronic myeloid leukemia. This study concluded that drug interactions were found in a significant number of patients, with mild side effects. Some background Imatinib (Gleevec) and similar drugs are the...
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In a nutshell This study aimed to measure the effectiveness of bendamustine and rituximab as salvage treatment in patients with chronic lymphocytic leukemia. This study concluded that bendamustine and rituximab are as effective as ibrutinib as salvage treatment in these patients. Some background The standard treatment for chronic lymphocytic...
Read MoreIn a nutshell This paper compared ponatinib (Iclusib) and stem cell transplantation in leukemia patients with an abnormality on the T315I gene. Patients with acute lymphoblastic leukaemia (ALL) positive for the Philadelphia chromosome and patients with chronic myeloid leukaemia (CML) were studied. Authors reported improved survival with...
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In a nutshell This review discussed the role of stem cell transplantation in patients with chronic myeloid leukemia. Some background Stem cell (immature blood cell) transplantation (SCT) has had a long history in the treatment of chronic myeloid leukemia (CML). Patients who have a matched donor (someone who is a close genetic match, such as a...
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