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Confined or spread disease-Spread with distant metastasis Posts on Medivizor

Tucatinib plus trastuzumab and capecitabine preserves health-related quality of life in patients with metastatic HER2-positive breast cancer.

Tucatinib plus trastuzumab and capecitabine preserves health-related quality of life in patients with metastatic HER2-positive breast cancer.

Posted by on Sep 5, 2021 in Breast cancer | 0 comments

In a nutshell This study evaluated the impact of tucatinib (Tukysa) in combination with trastuzumab (Herceptin) and capecitabine (Xeloda) on health-related quality of life (HR-QoL) in patients with metastatic human epidermal growth factor (HER2)-positive breast cancer (BC). The data showed that this combination preserved HR-QoL in these patients. Some...

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Evaluating the effectiveness and safety of different bevacizumab schedules in combination with chemotherapy for the treatment of patients with metastatic colorectal cancer.

Evaluating the effectiveness and safety of different bevacizumab schedules in combination with chemotherapy for the treatment of patients with metastatic colorectal cancer.

Posted by on Aug 29, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of bevacizumab (Avastin) administered either on the same day or a few days before chemotherapy for the treatment of patients with metastatic colorectal cancer (mCRC). The data showed that bevacizumab administered 4 days before chemotherapy significantly improved overall survival with...

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Is surgery of metastases effective after failure of modern whole-body treatments in patients with advanced melanoma?

Is surgery of metastases effective after failure of modern whole-body treatments in patients with advanced melanoma?

Posted by on Aug 22, 2021 in Melanoma | 0 comments

In a nutshell This study looked at the use of surgery for spread disease (metastases) in patients with advanced melanoma when other whole-body treatments had failed. It found that surgical removal of metastases improved the outcomes of these patients. Some background Advanced melanoma can spread to many places in the body. It is usually...

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What is the effective dose of ipilimumab combined with standard dose of pembrolizumab in patients with advanced melanoma?

What is the effective dose of ipilimumab combined with standard dose of pembrolizumab in patients with advanced melanoma?

Posted by on Aug 8, 2021 in Melanoma | 0 comments

In a nutshell The study aimed to evaluate the effectiveness and safety of combining standard-dose pembrolizumab (PEM; Keytruda) with two different doses of ipilimumab (IPI; Yervoy) in patients with advanced melanoma. The study concluded that 200 mg PEM plus 50 mg of IPI showed good effectiveness and reduced toxicity compared to 100 mg...

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Is pyrotinib with vinorelbine effective in treating HER2+ metastatic breast cancer?

Is pyrotinib with vinorelbine effective in treating HER2+ metastatic breast cancer?

Posted by on Jul 21, 2021 in Breast cancer | 0 comments

In a nutshell This study was carried out to examine the safety and effectiveness of pyrotinib (Irene) in combination with vinorelbine (Navelibine) is in treating metastatic breast cancer (BC). The authors found that this treatment combination showed promising results and was well tolerated in these patients.  Some background BC is...

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Is pembrolizumab plus ipilimumab combination therapy safe and effective for the treatment of advanced melanoma after failure of anti-PD-1/L1 therapy?

Is pembrolizumab plus ipilimumab combination therapy safe and effective for the treatment of advanced melanoma after failure of anti-PD-1/L1 therapy?

Posted by on Jul 11, 2021 in Melanoma | 0 comments

In a nutshell This study aimed to investigate the effectiveness and safety of combining pembrolizumab (PEM; Keytruda)) and ipilimumab (IPI; Yervoy) for the treatment of advanced-stage melanoma in patients that have progressed after previous PD-1/L1 therapy. The study concluded that this combination was well tolerated and improved the...

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Comparing the safety and effectiveness of pyrotinib versus trastuzumab etamsine for the treatment of HER2-positive metastatic breast cancer.

Comparing the safety and effectiveness of pyrotinib versus trastuzumab etamsine for the treatment of HER2-positive metastatic breast cancer.

Posted by on Jul 11, 2021 in Breast cancer | 0 comments

In a nutshell This study compared the safety and effectiveness between pyrotinib (SHR-1258) and trastuzumab emtansine (T-DM1; Kadcyla) in patients with HER2+ metastatic breast cancer (BC) after previous treatment with trastuzumab (Herceptin) and chemotherapy. The data showed that pyrotinib may be more effective than T-DM1 for these patients. Some...

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Percutaneous radiofrequency ablation improves the outcomes of patients with colorectal cancer liver metastases

Percutaneous radiofrequency ablation improves the outcomes of patients with colorectal cancer liver metastases

Posted by on Jul 9, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of percutaneous radiofrequency ablation (PRA) in the treatment of colorectal cancer (CRC) liver metastases (LM). Researchers suggested that PRA is a good and safe method for the treatment of these patients.  Some background CRC is a common cancer worldwide, affecting 4.3% of...

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Sacituzumab govitecan improves survival in metastatic triple-negative breast cancer.

Sacituzumab govitecan improves survival in metastatic triple-negative breast cancer.

Posted by on Jun 12, 2021 in Breast cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of sacituzumab govitecan (Trodelvy; SG) compared to chemotherapy in patients with relapsed or refractory metastatic triple-negative breast cancer (mTNBC). The data showed that SG significantly improved the survival outcomes of these patients compared to chemotherapy. Some background...

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Does adding chemotherapy after surgery for liver metastasis improve the long-term outcome of patients with colorectal cancer?

Does adding chemotherapy after surgery for liver metastasis improve the long-term outcome of patients with colorectal cancer?

Posted by on Jun 6, 2021 in Colorectal cancer | 0 comments

In a nutshell The study investigated the impact of adding chemotherapy after surgery to remove liver metastasis on the outcomes of patients with colorectal cancer (CRC). The study reported a significantly longer survival in patients undergoing further chemotherapy. Some background Up to 50% of patients with CRC develop...

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Chemotherapy delivered directly in the liver in patients with colorectal cancer that has spread to the liver.

Chemotherapy delivered directly in the liver in patients with colorectal cancer that has spread to the liver.

Posted by on May 16, 2021 in Colorectal cancer | 0 comments

In a nutshell The aim of this study was to evaluate if hepatic arterial infusion chemotherapy (HAIC) could be beneficial for patients with colorectal cancer (CRC) that has spread to the liver (liver metastasis; LM). The study found that HAIC improved the outcome of these patients. Some background CRC is one of the most common types of cancer...

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Searching for patients with solid tumors with abnormal genetic changes to trial an experimental medication

Searching for patients with solid tumors with abnormal genetic changes to trial an experimental medication

Posted by on Apr 30, 2021 in Breast cancer | 0 comments

In a nutshell This study is searching for participants with advanced solid tumors including breast cancer to examine the safety and effectiveness of experimental drug avapritinib (AYVAKIT). The main outcomes to be measured are the response to treatment and side effects. This trial is being conducted in Texas, US. The details Some cancers grow as a...

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