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Confined or spread disease-Spread with distant metastasis Posts on Medivizor

Looking for patients with advanced triple negative breast cancer to test an experimental drug with three functions

Posted by on Oct 31, 2019 in Breast cancer | 0 comments

In a nutshell This trial is examining the safety and effectiveness of experimental drug mRNA-2752 in patients with advanced triple-negative breast cancer. The main outcome of the trial will be the number of side effects experienced by patients and response to treatment. This trial is recruiting in the United States and Israel. The details...

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Encorafenib, cetuximab and binimetinib combined treatment improves survival of patients with advanced colorectal cancer

Posted by on Oct 31, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated whether treatment with encorafenib (Braftovi), binimetinib (Mektovi), and cetuximab (Erbitux) combined would increase survival in advanced colorectal cancer (CRC). Researchers suggested that this combined therapy increases the survival of patients with metastatic (spread to other parts of the...

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Comparing endocrine treatment versus chemotherapy for metastatic breast cancer

Posted by on Oct 22, 2019 in Breast cancer | 0 comments

In a nutshell This study compared hormone therapy and chemotherapy for the treatment of metastatic (cancer that has spread) breast cancer. The authors concluded that hormone therapy plus targeted therapy is better than chemotherapy for patients with metastatic breast cancer. Some background Different types of breast cancer have different receptors....

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Looking for patients with hormone-receptor positive metastatic breast cancer to test an experimental biological drug

Posted by on Sep 30, 2019 in Breast cancer | 0 comments

In a nutshell This study is examining the effectiveness of biological drug sacituzumab govitecan (IMMU-132) compared to standard treatments for patients with hormone receptor-positive metastatic breast cancer. The main outcomes that will be measured are cancer responsiveness to the drug and survival of patients without the cancer growing. This trial...

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Looking for participants with advanced colorectal cancer to test a combination therapy

Posted by on Sep 25, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 1/2 trial is examining the effectiveness of standard therapy alone or combined with new drugs as first line treatment for advanced colorectal cancer. The main outcome to be measured will be safety and tumor response to the treatment.  The details Colorectal cancer is one of the most common cancers worldwide. A significant...

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Treatment dose optimisation in patients with advanced colorectal cancer treated with regorafenib

Posted by on Sep 25, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of increasing doses of regorafenib (Stivarga) doses in patients with advanced colorectal cancer. Researchers suggested that this method with increasing doses should be used to assess the optimal dose for each patient. Some background Colorectal cancer is the third most common cancer...

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Looking for patients with advanced colorectal cancer to test an experimental treatment

Posted by on Sep 10, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 1/2 trial is examining the effectiveness of treatment with GB1275 alone or in combination with immunotherapy in patients with advanced solid tumors such as colorectal cancer. The main outcome to be measured will be dose toxicity and tumor response to the treatment. This study is being conducted in Tennessee and Texas, US. The...

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The effects of maintenance vs intermittent therapy in the treatment of advanced colorectal cancer

Posted by on Sep 4, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effects of maintenance therapy (MT) compared to intermittent therapy (IT) for patients with metastatic (spread to other parts of the body) colorectal cancer. Researchers suggested that MT might improve the treatment of these patients. Some background Colorectal cancer is the second most common cancer...

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Internal selective radiotherapy improves the outcomes of patients with colorectal cancer liver metastasis

Posted by on Sep 2, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness of selective internal radiation therapy (SIRT) in the treatment of colorectal cancer liver metastasis (CRC-LM). Researchers suggested that adding this therapy to the treatment improves the outcomes of the treatment. Some background The liver is a common site for colorectal cancer metastasis...

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Side effects of ado-trastuzumab emtansine impacting outcomes in patients with HER2+ advanced breast cancer

Posted by on Aug 25, 2019 in Breast cancer | 0 comments

In a nutshell This study aimed to investigate the impact of early side effects requiring ado-trastuzumab emtansine dose interruptions or reductions on outcomes for patients with HER2+ advanced metastatic breast cancer.  This study concluded that these side effects do not impact the outcomes for these patients.   Some background...

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Looking for participants with metastatic melanoma to test a new immunotherapy

Posted by on Aug 14, 2019 in Melanoma | 0 comments

In a nutshell This phase 1 trial is examining the effectiveness of personalized tumor antigens (PTA) in the treatment of different advanced tumors. The main outcomes to be measured will be side effects and disease control. This study is being conducted in Arizona, California, Louisiana and New Jersey, US. The details While the tumor cells are growing,...

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