In a nutshell This study wanted to see how well two medications worked in treating advanced triple negative breast cancer, atezolizumab (Tecentriq) and nab-paclitaxcel (Abraxane). The study found that using these two medications together improved survival in these patients. Some background Triple-negative breast cancer (TNBC) is breast cancer...
Read MoreConfined or spread disease-Spread to regional lymph nodes Posts on Medivizor
Surgery to remove the main tumor in patients with breast cancer that has spread
In a nutshell This study wanted to find out if removing the main tumor in women with cancer that has spread to other organs leads to greater survival than not removing the main tumor. The study found that the patients who had the surgery survived 47% longer than patients without the surgery. Some background Breast cancer can sometimes be caught quite...
Read MoreLooking for patients with triple negative inoperable breast cancer to test a new treatment option atezolizumab
In a nutshell This trial is examining the effectiveness of atezolizumab (Tecentriq) when used with chemotherapy in patients with inoperable, recurrent triple-negative breast cancer. The main outcome to be measured will be the overall survival (time from treatment until death from any cause) of participants. The...
Read MoreLooking for patients with HER2 negative HR positive advanced breast cancer to test tesetaxel
In a nutshell This trial is examining the effectiveness of tesetaxel plus a reduced dose of capecitabine for hormone receptor (HR) positive/HER2 negative advanced breast cancer. The main outcome to be measured will be progression free survival (time from treatment until disease progression). The details Breast cancer is classified into...
Read MoreLooking for patients with triple negative breast cancer to test atezolizumab
In a nutshell This trial is examining the effectiveness of chemotherapy and atezolizumab (Tecentriq), given before surgery, for triple negative breast cancer. The main outcomes to be measured will be response in the breast tissue and lymph nodes and survival. The details Triple negative breast cancer is not dependent on the HER2 receptors or...
Read MoreLooking for women with metastatic breast cancer to evaluate whole, plant based diets
In a nutshell This trial is examining the effectiveness of a whole food diet for women with stable metastatic (spread) breast cancer currently undergoing treatment. The main outcomes to be measured will be the recruitment of patients approached, adherence to diet and change in symptoms and biomarkers. This study is being...
Read MoreLooking for participants with advanced melanoma to test the effectiveness of a combined immunotherapy
In a nutshell This phase 2 trial aims to test the effectiveness of the combined treatment of three different immunotherapies. The main outcomes of this trial will be the tumor response to the treatment and the overall survival. The details Immunotherapies stimulate the immune system to attack and kill cancer cells the way it would a virus or...
Read MoreNivolumab treatment is associated with an improved survival in advanced melanoma
In a nutshell This study investigated the effect of nivolumab (Opdivo) in patients with progressive melanoma after ipilimumab (Yervoy) treatment. Researchers suggested that nivolumab treatment is associated with better response compared with chemotherapy. Some background Recent new therapies, such as immunotherapy, have changed the treatment of...
Read MoreHow safe and effective is chemotherapy given through the limb in elderly melanoma patients?
In a nutshell This study looked at the safety and effectiveness of isolated limb infusion in elderly patients with melanoma of the skin on a limb (arm/leg) that could not be surgically removed. The study found isolated limb infusion to be safe and effective in elderly patients. Some background lsolated limb perfusion (ILP) is a method of...
Read MoreFulvestrant: an option for estrogen-receptor positive breast cancer that has spread
In a nutshell This study aimed to compare fulvestrant (Faslodex) to other standard endocrine agents in patients with advanced hormone sensitive breast cancer. This study concluded that fulvestrant was as effective as the available standard endocrine agents. Some background Advanced hormone sensitive breast cancer (BC) is cancer that has...
Read MoreIs abemaciclib combined with fulvestrant effective in women with HR positive advanced breast cancer?
In a nutshell This study aimed to compare the effectiveness of the combination of fulvestrant (Faslodex) and abemaciclib to fulvestrant alone in patients with advanced breast cancer. This study concluded that the combination of fulvestrant and abemaciclib had improved outcomes for patients when compared to fulvestrant alone. Some background...
Read MoreThe role of dexamethasone mouthwash in preventing everolimus-related stomatitis in women with breast cancer
In a nutshell This study investigated the use of dexamethasone (Ozurdex) mouthwash for preventing stomatitis in patients with breast cancer(BC). The use of dexamethasone oral solution was found to significantly reduce the incidence and severity of stomatitis. Some background Everolimus (Afinitor) and exemestane (Aromasin) are mTOR inhibitors...
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