Confined or spread disease-Spread to regional lymph nodes - Page 3 of 13 Posts on Medivizor
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Confined or spread disease-Spread to regional lymph nodes Posts on Medivizor

Does it matter how much healthy tissue is removed during surgery for patients with breast cancer who received chemotherapy first?

Does it matter how much healthy tissue is removed during surgery for patients with breast cancer who received chemotherapy first?

Posted by on Apr 18, 2020 in Breast cancer | 0 comments

In a nutshell This study examined if there was a difference in patients with breast cancer first treated with chemotherapy that had a wide or narrow margin of healthy tissue removed during surgery. The results showed that the outcomes were similar regardless of how much healthy tissue was removed. Some background Traditionally, mastectomy (the...

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Long-term outcomes of pertuzumab added to trastuzumab and docetaxel treatment for patients with advanced HER2-positive breast cancer

Posted by on Apr 7, 2020 in Breast cancer | 0 comments

In a nutshell This study looked at whether pertuzumab (Perjeta) benefits patients with metastatic HER2-positive breast cancer when added to trastuzumab (Herceptin) and docetaxel (Taxotere) treatment. They found that adding pertuzumab improved long-term patient outcomes. Some background Breast cancer can now be tested for some of the signals involved...

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Palbociclib and exemestane versus capecitabine in premenopausal women with hormone receptor-positive metastatic breast cancer

Palbociclib and exemestane versus capecitabine in premenopausal women with hormone receptor-positive metastatic breast cancer

Posted by on Dec 7, 2019 in Breast cancer | 0 comments

In a nutshell This study aimed to compare the safety and effectiveness of palbociclib and endocrine therapy to capecitabine chemotherapy in premenopausal women with hormone receptor-positive, HER2-negative metastatic breast cancer.  This study concluded that palbociclib and endocrine therapy is more effective than...

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Comparing endocrine treatment versus chemotherapy for metastatic breast cancer

Posted by on Oct 22, 2019 in Breast cancer | 0 comments

In a nutshell This study compared hormone therapy and chemotherapy for the treatment of metastatic (cancer that has spread) breast cancer. The authors concluded that hormone therapy plus targeted therapy is better than chemotherapy for patients with metastatic breast cancer. Some background Different types of breast cancer have different receptors....

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Ending trastuzumab treatment in patients with HER2-positive metastatic breast cancer who are in radiological complete remission

Ending trastuzumab treatment in patients with HER2-positive metastatic breast cancer who are in radiological complete remission

Posted by on Oct 20, 2019 in Breast cancer | 0 comments

In a nutshell This study aimed to investigate the effect of stopping trastuzumab treatment in patients with HER2-positive metastatic breast cancer with radiological complete remission.   This study concluded that trastuzumab may be safely stopped in selected patients with radiological complete...

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Looking for patients with advanced triple negative breast cancer to test a new treatment

Looking for patients with advanced triple negative breast cancer to test a new treatment

Posted by on Sep 10, 2019 in Breast cancer | 0 comments

In a nutshell This phase 1/2 trial is examining the effectiveness of treatment with GB1275 alone or in combination with immunotherapy in patients with solid tumors such as triple-negative breast cancer. The main outcome to be measured will be dose toxicity and tumor response to the treatment. This study is being conducted in Tennessee and Texas, US. The...

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Looking for patients with advanced melanoma to test a combination of antibody and enzyme drugs

Looking for patients with advanced melanoma to test a combination of antibody and enzyme drugs

Posted by on Aug 31, 2019 in Melanoma | 0 comments

In a nutshell This trial is examining if adding antibody drug rituximab (Rituxan) and enzyme drug hyaluronidase human (Hycela) can increase the effectiveness of the standard treatment for melanoma. The main outcomes of this trial will be to examine the side effects experienced by patients and tumor response. This study is recruiting in...

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Searching for patients with advanced triple-negative breast cancer to test a new combination treatment

Posted by on Aug 22, 2019 in Breast cancer | 0 comments

In a nutshell This phase 1b/2 trial will investigate the safety of cabozantinib (Cabometyx) with or without atezolizumab (Tecentriq) in patients with advanced solid tumors. The main outcomes will be maximum tolerated dose (MTD) and overall response rate (ORR). The details Advanced cancers have limited treatment options. Surgery may...

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