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Confined or spread disease-Spread to regional lymph nodes Posts on Medivizor

Timing of treatment with ipilimumab and nivolumab in patients with stage 3 melanoma

Posted by on Jul 8, 2019 in Melanoma | 0 comments

In a nutshell This study wanted to find out what the best timing is for treating patients with stage 3 melanoma with ipilimumab (Yervoy) and nivolumab (Opdivo). The study found that the best timing was two cycles of ipilimumab 1 mg/kg plus nivolumab 3 mg/kg every three weeks. Some background Ipilimumab and nivolumab are medications used to treat...

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Looking for patients with advanced triple negative breast cancer to test a new drug

Posted by on Jun 28, 2019 in Breast cancer | 0 comments

In a nutshell This phase 1 study will investigate the dose range and effectiveness of an experimental drug, XmAb23104, in the treatment of advanced breast cancer and other solid tumors.  The main outcome will be the safety and tolerability of XmAb23104. This trial is recruiting in Georgia, Texas, and Virginia, the United States. The details...

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Searching for patients with triple negative breast cancer to test a new medication

Posted by on Apr 22, 2019 in Breast cancer | 0 comments

In a nutshell This phase 3 trial will investigate the safety and effectiveness of adagloxad simolenin (AGS)/OBI-821 in triple-negative breast cancer (TNBC). The main outcome will be a change in survival without invasive disease. The details Breast cancer (BC) is one of the most common cancers. BC treatment depends on the tumor type....

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Olaparib for treating breast cancer that has spread

Posted by on Mar 5, 2019 in Breast cancer | 0 comments

In a nutshell This study determined whether treating breast cancer that has spread (metastatic) with olaparib (Lynparza) resulted in better outcomes and fewer side effects compared to chemotherapy. The study found that treatment with olaparib led to similar survival outcomes compared to chemotherapy.  Some background There are...

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Searching for patients with untreated advanced melanoma to trial a new personalized cancer vaccine

Posted by on Feb 23, 2019 in Melanoma | 0 comments

In a nutshell This trial aims to see if combining two medications, pembrolizumab (Keytruda) and RO7198457 (a new experimental vaccine) is better than just using pembrolizumab in treating advanced melanoma that has not been treated before. The main outcome that will be measured is how long the patients go without cancer growing. The study is being...

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Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer.

Posted by on Nov 11, 2018 in Breast cancer | 0 comments

In a nutshell This study wanted to see how well two medications worked in treating advanced triple negative breast cancer, atezolizumab (Tecentriq) and nab-paclitaxcel (Abraxane).  The study found that using these two medications together improved survival in these patients. Some background Triple-negative breast cancer (TNBC) is breast cancer...

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Surgery to remove the main tumor in patients with breast cancer that has spread

Posted by on Oct 18, 2018 in Breast cancer | 0 comments

In a nutshell This study wanted to find out if removing the main tumor in women with cancer that has spread to other organs leads to greater survival than not removing the main tumor. The study found that the patients who had the surgery survived 47% longer than patients without the surgery. Some background Breast cancer can sometimes be caught quite...

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