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Confined or spread disease-Spread to regional lymph nodes Posts on Medivizor

Comparing endocrine treatment versus chemotherapy for metastatic breast cancer

Posted by on Oct 22, 2019 in Breast cancer | 0 comments

In a nutshell This study compared hormone therapy and chemotherapy for the treatment of metastatic (cancer that has spread) breast cancer. The authors concluded that hormone therapy plus targeted therapy is better than chemotherapy for patients with metastatic breast cancer. Some background Different types of breast cancer have different receptors....

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Ending trastuzumab treatment in patients with HER2-positive metastatic breast cancer who are in radiological complete remission

Posted by on Oct 20, 2019 in Breast cancer | 0 comments

In a nutshell This study aimed to investigate the effect of stopping trastuzumab treatment in patients with HER2-positive metastatic breast cancer with radiological complete remission.   This study concluded that trastuzumab may be safely stopped in selected patients with radiological complete...

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Looking for patients with advanced triple negative breast cancer to test a new treatment

Posted by on Sep 10, 2019 in Breast cancer | 0 comments

In a nutshell This phase 1/2 trial is examining the effectiveness of treatment with GB1275 alone or in combination with immunotherapy in patients with solid tumors such as triple-negative breast cancer. The main outcome to be measured will be dose toxicity and tumor response to the treatment. This study is being conducted in Tennessee and Texas, US. The...

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Looking for patients with advanced melanoma to test a combination of antibody and enzyme drugs

Posted by on Aug 31, 2019 in Melanoma | 0 comments

In a nutshell This trial is examining if adding antibody drug rituximab (Rituxan) and enzyme drug hyaluronidase human (Hycela) can increase the effectiveness of the standard treatment for melanoma. The main outcomes of this trial will be to examine the side effects experienced by patients and tumor response. This study is recruiting in...

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Searching for patients with advanced triple-negative breast cancer to test a new combination treatment

Posted by on Aug 22, 2019 in Breast cancer | 0 comments

In a nutshell This phase 1b/2 trial will investigate the safety of cabozantinib (Cabometyx) with or without atezolizumab (Tecentriq) in patients with advanced solid tumors. The main outcomes will be maximum tolerated dose (MTD) and overall response rate (ORR). The details Advanced cancers have limited treatment options. Surgery may...

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Timing of treatment with ipilimumab and nivolumab in patients with stage 3 melanoma

Posted by on Jul 8, 2019 in Melanoma | 0 comments

In a nutshell This study wanted to find out what the best timing is for treating patients with stage 3 melanoma with ipilimumab (Yervoy) and nivolumab (Opdivo). The study found that the best timing was two cycles of ipilimumab 1 mg/kg plus nivolumab 3 mg/kg every three weeks. Some background Ipilimumab and nivolumab are medications used to treat...

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Looking for patients with advanced triple negative breast cancer to test a new drug

Posted by on Jun 28, 2019 in Breast cancer | 0 comments

In a nutshell This phase 1 study will investigate the dose range and effectiveness of an experimental drug, XmAb23104, in the treatment of advanced breast cancer and other solid tumors.  The main outcome will be the safety and tolerability of XmAb23104. This trial is recruiting in Georgia, Texas, and Virginia, the United States. The details...

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