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Confined or spread disease-Spread beyond the prostate gland Posts on Medivizor

Looking for patients with advanced prostate cancer to test a new treatment

Posted by on Sep 10, 2019 in Prostate cancer | 0 comments

In a nutshell This phase 1/2 trial is examining the effectiveness of treatment with GB1275 alone or in combination with immunotherapy in patients with advanced solid tumors such as prostate cancer. The main outcome to be measured will be dose toxicity and tumor response to the treatment. This study is being conducted in Tennessee and Texas, US. The...

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Evaluating enzalutamide plus androgen deprivation therapy to treat metastatic prostate cancer

Posted by on Aug 31, 2019 in Prostate cancer | 0 comments

In a nutshell This study aimed to examine the effectiveness and safety of enzalutamide (Xtandi) with androgen deprivation therapy (ADT) in metastatic prostate cancer. This study found that this combination was associated with longer progression-free and overall survival compared to ADT alone. Some background Patients...

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Looking for patients with advanced prostate cancer to test a new drug

Posted by on Jul 21, 2019 in Prostate cancer | 0 comments

In a nutshell This phase 1 trial will investigate the safety of an experimental drug, XmAb22841 (XmAb), to treat advanced cancer. The main outcome will be the safety and tolerability of XmAb. This study is recruiting in Georgia and Texas, USA. The details Advanced cancer can be difficult to treat. New drugs are being developed to address this. Immune...

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Searching for patients with metastatic castration resistant prostate cancer to test a targeted therapy option

Posted by on Jun 24, 2019 in Prostate cancer | 0 comments

In a nutshell This phase 2 trial is examining the effectiveness and safety of trametinib (Mekinist) in patients with metastatic castration-resistant prostate cancer (mCRPC; prostate cancer which has spread from its original place to another area in the body and keeps growing even when the amount of testosterone in the body...

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Searching for patients with prostate cancer to test this new treatment combination

Posted by on Jun 24, 2019 in Prostate cancer | 0 comments

In a nutshell This phase 2 trial is examining the effectiveness and safety of navarixin (MK-7123) in combination with pembrolizumab (Keytruda) in patients with castration-resistant prostate cancer (CRPC; cancer that progresses after hormonal therapy). The main outcome to be measured will be the objective response rate (ORR; tumor shrinkage or...

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Long term outcomes of docetaxel-based chemotherapy with dexamethasone for advanced prostate cancer

Posted by on May 31, 2019 in Prostate cancer | 0 comments

In a nutshell This article investigated the safety and effectiveness of docetaxel (Taxotere)-based chemotherapy in combination with dexamethasone (Decadron) for the treatment of castration-resistant prostate cancer (CRPC). The authors concluded that this treatment combination is a safe and effective treatment option for...

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Abiraterone acetate plus prednisone: an evaluation of the long-term effectiveness in prostate cancer treated with hormonal therapy.

Posted by on May 18, 2019 in Prostate cancer | 0 comments

In a nutshell This study investigated if abiraterone acetate (Zytiga) and prednisone (Deltasone) added to androgen deprivation therapy (ADT) improve survival in patients with advanced prostate cancer. They found that this combination was effective at improving survival in these patients. Some background...

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The use of stereotactic radiotherapy in patients with metastatic prostate cancer.

Posted by on Apr 24, 2019 in Prostate cancer | 0 comments

In a nutshell This study examined stereotactic body radiotherapy (SBRT) as a treatment for advanced prostate cancer. This study concluded that SBRT may be effective in the treatment of these patients. Some background Oligometastatic prostate cancer is cancer that is no longer confined to the prostate gland. However, it has not yet become...

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How effective is radiotherapy for the treatment of advanced prostate cancer?

Posted by on Apr 13, 2019 in Prostate cancer | 0 comments

In a nutshell This study investigated the effectiveness of prostate radiotherapy (RT) in prostate cancer (PC). They found that prostate RT may improve survival in men with PC and fewer than 5 bone metastasis (cancer that has spread to the bones).  Some background Prostate cancer (PC) is a common and treatable cancer in men. One common type...

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Looking for men with newly diagnosed advanced prostate cancer to test treatment combinations

Posted by on Mar 28, 2019 in Prostate cancer | 0 comments

In a nutshell This trial is examining the effectiveness of radical prostatectomy, in newly diagnosed advanced prostate cancer. The main outcome to be measured will be survival without the cancer worsening. This trial is recruiting in the United States. The details Androgens can cause the growth of prostate cancer cells. Antiandrogen therapy (ADT) may...

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