In a nutshell This study compared the effectiveness of functional and oncological outcomes of robotic-assisted (RA) and laparoscopic (Lap) radical prostatectomy (RP; removal of the prostate) in localized and locally advanced prostate cancer (PCa). the study concluded that RARP was similarly effective and had better urinary and sexual outcomes...
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In a nutshell This article reviewed treatment options for patients with high-risk prostate cancer. Some background Prostate cancer is a cancer that starts in the prostate gland. There are different types of treatment for patients with prostate cancer. Treatment choice depends on disease stage or whether the cancer has spread to other parts of the...
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In a nutshell This study compared the safety and effectiveness of short-term androgen deprivation therapy (ADT) combined with radiotherapy (RT) in patients who underwent radical prostatectomy (RP). The main finding was that the combination of ADT and RT reduced the risk of recurrence and disease progression in these patients. Some background RP is...
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In a nutshell This study aims to examine the effectiveness of niraparib (Zejula) combined with hormone therapy and radiotherapy to treat patients with high-risk prostate cancer. The main outcome to be measured will be how long patients remain cancer-free. This study is recruiting in Philadelphia, PA. The details Prostate cancer occurs mostly...
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In a nutshell This article investigated the toxicity of intensity-modulated radiation therapy (IMRT) to the prostate and pelvic lymph nodes (PPLN-IMRT) compared with prostate-only (PO-IMRT) in high-risk prostate cancer (PC). The authors concluded that both treatments had similar toxicity rates in these patients. Some background...
Read MoreIn a nutshell This trial is looking at using proton-based radiation therapy to target high-risk prostate tumors. The main outcome to be measured is the rate of recurrence 5 years after the end of the treatment. This study is taking place in Florida, USA. The details Prostate cancer can be treated by medication, surgery or radiation....
Read MoreIn a nutshell This study aimed to evaluate whole pelvic radiotherapy (WPRT) compared to prostate only radiotherapy (PORT) with hormonal therapy (HT) before or after radiation for patients with intermediate- or high-risk prostate cancer. This study found that HT before radiotherapy and WPRT had superior long-term survival without cancer growing or...
Read MoreIn a nutshell This study aimed to investigate the long-term effects of two treatment combinations for advanced prostate cancer. This study found that surgery and radiotherapy had improved overall survival in comparison with radiotherapy plus androgen deprivation therapy (ADT) in these patients, but with higher rates of side-effects. Some background...
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In a nutshell This study examined the potential benefit of early intensive hormonal therapy (combined androgen blockade) in men with high-risk local prostate cancer, given before surgery. Researchers concluded that intensive hormone therapy may be more effective than standard treatment in reducing androgen levels, but seldom results in complete tumor...
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In a nutshell This study investigated if measuring the levels of prostate specific antigen (PSA) after cancer therapy could indicate a cure or if the patient should be considered for long term androgen deprivation (suppression) therapy. The main finding was that lower PSA blood levels predict better survival in patients with prostate cancer. Some...
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In a nutshell This review evaluated the safety and efficacy of focal salvage ablative therapy for the treatment of patients with prostate cancer recurrence (return of the cancer) after radiation therapy. Some background Radiation therapy (RT) is often used to treat early stage prostate cancer. However, after RT, the cancer may recur, locally...
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In a nutshell This review investigated treatment options following biochemical recurrence after primary treatment for prostate cancer. Some background Prostate cancer can be treated using a variety of methods, the most common being partial or full removal of the prostate gland, a procedure known as a prostatectomy. Other treatments include...
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