In a nutshell This study evaluated prostate-specific mortality risk based on PSA (prostate specific antigen) levels in men with high-grade disease. Authors reported increased mortality risk with lower PSA levels in men with high-grade disease. A decreased mortality risk was observed with lower PSA levels in men with low-grade disease. Some background...
Read MoreConfined or spread disease-Confined to the prostate gland Posts on Medivizor
Can immune cells predict disease recurrence after prostate surgery?
In a nutshell This study evaluated whether the neutrophil-to-lymphocyte ratio (NLR) can predict disease recurrence after treatment with prostate surgery. Researchers reported a strong association between high NLR and disease recurrence after prostate surgery. Some background Neutrophils are cells that are involved in inflammation (reaction to...
Read MoreSearching for men with early stage prostate cancer to test a short course of very focused radiation therapy
In a nutshell This phase 1/2 trial aims to evaluate the effectiveness of a short course of very focused radiation therapy in the treatment of early stage prostate cancer. The main outcome to be investigated is side effects and treatment response. The trial is recruiting in San Diego, California (USA). The details External beam radiation therapy...
Read MoreOther medical conditions can affect cancer progression during active surveillance
In a nutshell This study examined the relationship between comorbidities (other medical conditions) and cancer progression during active surveillance. Researchers reported that progression is more likely among men with 2 or more comorbidities. Some background Active surveillance of prostate cancer refers to actively monitoring tumor growth...
Read MoreAre focal therapies an option for recurrent cancer?
In a nutshell This review examined the safety and effectiveness of focal therapies for recurrent localized prostate cancer. The authors concluded that there is early evidence to suggest that focal therapies are well-tolerated and effective for recurrent localized prostate cancer. Some background Radiation therapy is a common treatment for...
Read MoreHigh-intensity focused ultrasound for localized prostate cancer
In a nutshell This study investigated the safety and effectiveness of high-intensity focused ultrasound (HIFU) in treating localized prostate cancer. Researchers concluded that HIFU is an effective treatment option, particularly for men not suitable for surgery or radiation therapy. Some background Localized prostate cancer is cancer that is...
Read MoreThe risk of colorectal cancer after prostate cancer diagnosis
Published By : Cancer Date : Feb 25, 2016 Original Title : Risk of colorectal cancer after the diagnosis of prostate cancer: A population-based study. ...
Read MoreSearching for men with PSA levels rising after primary treatment to test an immunotherapy vaccine
In a nutshell This phase II trial aims to evaluate the effectiveness of a personalized peptide-based vaccine (Multi-Epitope TARP) on preventing progression of localized prostate cancer. The main outcome to be investigated is disease progression based on blood tests. The trial is recruiting in Maryland (USA). The details Immunotherapy has recently...
Read MoreGuidelines for the active surveillance of localized prostate cancer
In a nutshell This review summarized guidelines for the active surveillance of localized prostate cancer. The authors reported that active surveillance is a suitable strategy for the management of most low-risk prostate cancers provided appropriate monitoring protocols are followed. Some background Active surveillance refers to actively monitoring...
Read MoreLow-risk prostate cancer: Predictors of disease progression during active surveillance
In a nutshell This review examined predictors of disease progression in low-risk prostate cancer during active surveillance. Researchers concluded that certain blood markers, biopsy results, and ethnicity could help predict which patients were more likely to experience disease progression. Some background Active surveillance of prostate...
Read MoreCombined androgen blockade before surgery for local cancers
In a nutshell This study examined the potential benefit of early intensive hormonal therapy (combined androgen blockade) in men with high-risk local prostate cancer, given before surgery. Researchers concluded that intensive hormone therapy may be more effective than standard treatment in reducing androgen levels, but seldom results in complete tumor...
Read MoreA better way to preserve continence? A new technique for prostatectomy
In a nutshell This study examined the effects of total anatomical reconstruction (TAR) during robot-assisted radical prostatectomy on recovery of urinary continence. Some background Urinary incontinence is a potential side effect of radical prostatectomy (removal of the prostate gland) that can impair a patient’s quality of life...
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