In a nutshell This trial aims to examine stereotactic radiosurgery guided by an imaging technique in treating low- to intermediate-risk prostate cancer. The main outcome to be investigated is treatment-related side effects and treatment response. The trial is recruiting in Ohio (USA). The details Stereotactic radiosurgery (SRS) uses a specially...
Read MoreConfined or spread disease-Confined to the prostate gland Posts on Medivizor
Primary prostate cancer treatment improves urinary symptoms in men with pre-treatment urinary complications
In a nutshell The authors aimed to determine the benefits and drawbacks of prostate cancer treatment in patients who suffer from pre-treatment urinary problems. The authors concluded that patients with pre-treatment urinary problems benefitted from prostate surgery. Some background Prostate surgery involves surgically removing the prostate...
Read MoreDifferent radiation therapy schedules: Hyopfractioned EBRT is as effective as standard EBRT
In a nutshell This study compared the safety and effectiveness of external beam radiation therapy (EBRT) and hypofractioned EBRT (H-EBRT) for localized prostate cancer. Researchers reported no differences in survival or disease recurrence rates between high H-EBRT and EBRT. Some background Radiation therapy is a common treatment for localized...
Read MoreImprovement of urinary tract symptoms in patients who underwent robot-assisted prostate surgery
In a nutshell The main aim of this study was to assess urinary tract symptoms (LUTS) in prostate cancer patients following robotic-assisted laparoscopic prostatectomy (RALP). The authors concluded that the majority of patients with moderate to severe LUTS improved significantly following RALP. Some background RALP is a relatively new...
Read MoreTwo new predictors of cancer recurrence after surgery: Perineural invasion and lymphovascular invasion
In a nutshell This study examined two new predictors of prostate cancer recurrence – perineural invasion (PNI) and lymphovascular invasion (LVI). Researchers reported increased recurrence risk after prostate surgery if patients show PNI or LVI before surgery, particularly if both were present. Some background Localized (confined)...
Read MoreExamining high-intensity focused ultrasound for unilateral prostate cancer
In a nutshell This study examined the effectiveness of high-intensity focused ultrasound (HIFU) in treating unilateral prostate cancer (only affecting one side). Authors reported good cancer control and a low rate of side effects. Some background Advances in cancer screening methods have led to earlier diagnoses of prostate cancer. Most are...
Read MoreExamining the benefits of combining hormone therapy and radiation therapy
In a nutshell This study examined the evidence for combining androgen deprivation therapy (ADT) with radiation therapy for the treatment of high-risk localized prostate cancer. Authors concluded that the combined therapy approach was associated with a survival advantage for intermediate- and high-risk patients. Some background ADT is a type...
Read MoreHyopfractioned or standard external beam radiation therapy – which is better?
In a nutshell This study compared external beam radiation therapy (EBRT) and hypofractioned EBRT (H-EBRT) for low-risk localized prostate cancer. Researchers reported no differences in disease progression or survival. However, an increase in side effects was observed with H-EBRT. Some background Radiation therapy is a common treatment for...
Read MoreHigh-risk prostate cancer: Surgery also a good treatment option for older men
In a nutshell This study examined outcomes of different treatment options among older men (aged 70 or older) with high-risk prostate cancer. Authors reported lower disease recurrence rates for prostate surgery compared to radiation and radiation with hormone therapy. Some background Prostate surgery and radiation therapy are both common treatment...
Read MoreCancer cells left behind: Even close surgical margins increase the risk of recurrence
In a nutshell This study investigated the risk of disease recurrence after prostate surgery based on surgical margins. Authors reported an increased risk of disease recurrence among men with close surgical margins. Some background Removal of the prostate gland is a common treatment of localized (confined) prostate cancer. Prostate surgery is...
Read MoreFactors important in upgrading from low-risk prostate cancer
In a nutshell This study examined factors important in upgrading from low-risk prostate cancer. Authors reported that age, tissue samples, and blood test results are strong predictors of upgrading from low-risk prostate cancer. Some background Most men diagnosed with prostate cancer are categorized as low risk. Low-risk prostate cancer is...
Read MoreApalutamide: Early results of a new type of secondary hormone therapy
In a nutshell This study examined the benefit of adding apalutamide (JNJ 56021927) to standard hormone therapy in men with castration-resistant prostate cancer (CRPC). Researchers reported preliminary evidence for apalutamide as a safe and effective additional hormone therapy for high-risk CRPC. Some background Hormone therapy is the standard of...
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