In a nutshell This study looked at men with prostate cancer undergoing active surveillance, and tried to show which characteristics were related with an increased risk of cancer progression. Some background Prostate cancer is the uncontrolled growth and division of prostate cells. This growth can be slow and sometimes harmless, so in the...
Read MoreConfined or spread disease-Confined to the prostate gland Posts on Medivizor
The risk of adverse events after diagnosis of prostate cancer
In a nutshell This article looked at the risk of adverse events such as heart disease, blood clots, strokes and fractures in patients diagnosed with prostate cancer. Some background Treatments for prostate cancer can result in numerous side effects. For example, endocrine (hormonal) treatments can result in low bone density (weak bones prone to...
Read MoreComparing the benefits of radiotherapy versus a “wait and see” approach for patients with stage III prostate cancer who were treated with radical prostatectomy
In a nutshell The present study evaluated whether patients with stage III prostate cancer (PCa) who underwent radical prostatectomy (RP) would benefit from further radiotherapy (RT), as opposed to the "wait and see" approach. There was a 21% increase in survival with no cancer progression in patients who received additional RT. Some...
Read MoreThe impact of 6 vs 18 months of androgen-suppression therapy, with or without Zolendronic Acid, on quality of life in men with prostate cancer
In a nutshell This clinical trial evaluated the quality of life of men with locally advanced prostate cancer (PCa) treated with Leuprorelin and radiotherapy, with or without Zolendronic Acid (ZA). Quality of life measures improved with shorter duration of Leuprorelin treatment, regardless of combining ZA. Some background Prostate cancer...
Read MoreSafety and efficacy of radical prostatectomy for men with locally recurrent prostate cancer
In a nutshell The present review evaluated the efficacy, safety and complications of salvage radical prostatectomy in patients with locally recurrent prostate cancer, and sought for the ideal candidates for this procedure. Some background Prostate cancer (PCa) is the most common type of cancer in men. Treatment options for PCa which is confined to...
Read MoreTargeting prostate cancer with gold nanoparticles
This article presents the novel concept of treating prostate cancer with radioactive gold nanoparticles. Nanoparticles are extremely small engineered structures that can be used to deliver treatments to otherwise inaccessible areas of the body. Radiation therapy for prostate cancer is currently given using many techniques, each of them having...
Read MoreEvaluating quality of life and adverse effects of proton therapy in young men with prostate cancer
The present study evaluated the quality of life and adverse effects for patients younger than 60 with prostate cancer following proton therapy. The main findings were that young prostate cancer patients treated with proton therapy have great outcomes with respect to urinary and sexual function. The prostate is a small gland only found in men that has...
Read MoreRisks of Incontinence and Sexual Dysfunction following Robotic or Open surgical removal of the prostate : A Comparison study
In a nutshell The present study compared the risks of urinary incontinence (loss of bladder control) and sexual dysfunction following two techniques of radical prostatectomy (complete surgical removal of the prostate gland): traditional open procedure versus robotic-minimally invasive surgery. Main findings: the risks tested were comparably...
Read MoreFocal Ultrasound-based therapy for prostate cancer as means to reduced genito-urinary side effects
In a nutshell This study evaluated whether focal Ultrasound-based therapy of individual cancer lesions can minimize the side effects associated with radical therapy that involves the whole prostate gland. Main findings: Focused therapy directed into cancer tissues significantly reduces genitourinary side effects like urine-leakage and impotence. Some...
Read MoreRadiation therapy for prostate cancer: how long do urinary-related side effects last?
In a nutshell The present study examined the duration of urinary-related side effects resulting from radiation therapy. Mild to severe urinary side effects were found to last up to 10 years post radiation therapy. Some background Prostate cancer is a slow growing form of cancer that is often managed by active surveillance or observation (delayed...
Read MoreEvaluating survival rates in patients with prostate cancer treated with low-dose-rate brachytherapy
In a nutshell The present study evaluated survival rates in patients with prostate cancer (PC) treated with Low-dose-rate prostate brachytherapy (LDR-PB). The main findings were that LDR-PB alone or combined with hormone therapy offers excellent survival in PC patients. Some background Prostate cancer is the most common type of cancer in men....
Read MoreA new biomarker panel for the assessment of prostate cancer recurrence risk
In a nutshell The present study evaluated a new biomarker that could be used to predict recurrence of prostate cancer after surgical removal of the prostate gland (prostatectomy). Three proteins called Sp1/Sp3/FLIP, combined with the Gleason score were found highly prognostic in the prediction of recurrence, and can therefore help guiding the initial...
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