In a nutshell This study will investigate the effect of probiotics in the prevention of hypertension. The main outcome will be a change in blood pressure (BP) after 12 weeks of treatment. The details Hypertension is a common and serious condition. Managing blood pressure (BP) levels is very important. Uncontrolled high BP can lead to...
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Looking for patients with borderline hypertension to test a non-pharmacological treatment strategy
In a nutshell This phase clinical trial will investigate the effect of remote ischemic conditioning (RIC) in patients with borderline hypertension. The main outcome will be the change in blood pressure (BP) over 33 days. The details Hypertension or high blood pressure (BP) is a serious condition. Hypertension increases the risk of major events...
Read MoreLooking for patients with high blood pressure to test a combination of folic acid and a blood pressure-lowering medication
In a nutshell This study is examining the effectiveness of adding folic acid to enalapril maleate (Vasotec) for patients with high blood pressure. The main outcome that will be measured is the decrease in homocysteine levels, a marker of high blood pressure. The details High blood pressure or hypertension can lead to other illnesses...
Read MoreLooking for patients with high blood pressure to test a Chinese herbal medicine
In a nutshell This study is examining the effectiveness of a herbal Chinese traditional medicine for high blood pressure. The main outcome to be measured will be the change in blood pressure after 8 weeks. The details Hypertension can damage blood vessels, which can cause other health problems. These include stroke, heart attacks,...
Read MoreLooking for patients with high blood pressure to try a single-pill combination medication
In a nutshell This study is evaluating the safety and effectiveness of losartan (Cozaar) plus hydrochlorothiazide (Microzide) in a single tablet for treating high blood pressure. The main outcomes will be blood pressure control rate after treatment and the number of patients who experience side effects. The details High...
Read MoreLooking for patients with hypertension to try a long-acting medication (nifedipine GITS)
In a nutshell This study will evaluate the effectiveness of the nifedipine (Adalat) gastrointestinal therapeutic system (GITS) on lowering blood pressure in adults with hypertension. The main outcomes measured will be blood pressure levels at follow-up and the change in blood pressure from the beginning to the end of treatment. The details...
Read MoreLooking for patients with AML to try a combination treatment
In a nutshell This trial is evaluating the effectiveness of KRT-232 for the treatment of acute myeloid leukemia (AML). The main outcomes are the number of patients who achieve complete remission, and how many patients stop treatment due to side effects. This study is being conducted in Columbus, Ohio, United States. The details AML is a...
Read MoreSearching for patients to try a radiation treatment strategy for prostate cancer.
In a nutshell This trial is examining the effectiveness of ultra-high-dose hypofractionated or single-dose radiotherapy for intermediate (medium) risk prostate cancer. The main outcome that will be measured will be the number of patients that experience side effects. This study is being conducted in New York City, NY, the US. The details...
Read MoreLooking for patients with diabetes receiving insulin to test mobile app
In a nutshell This study is looking for patients with diabetes taking insulin to test a mobile app that helps patients understand how blood glucose levels change. The main outcome that will be measured is the average blood glucose level at the beginning versus the end of the study. This study is recruiting in Boston, MA, the US. The details...
Read MoreSearching for patients with type 1 diabetes to test once-daily vs thrice-daily oral insulin
In a nutshell This trial is testing the effectiveness of once-daily vs thrice-daily oral insulin in patients with type 1 diabetes (T1D). The main outcome is the amount of injected insulin used, and the second outcome is the amount of time blood glucose levels are within specific ranges. This study is being conducted in Orange County, California,...
Read MoreSearching for patients with relapsed or unresponsive small lymphocytic lymphoma to test an immune cell-stimulating treatment
In a nutshell This study is looking for patients with relapsed or unresponsive chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) to test IOV-2001, a treatment that boosts cancer-killing immune cells. The main outcome that will be measured is how well patients respond to treatment. This study is recruiting in Columbus, OH, the...
Read MoreSearching for patients with relapsed or unresponsive chronic lymphocytic leukemia to test an immune cell-stimulating treatment
In a nutshell This study is looking for patients with relapsed or unresponsive chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) to test IOV-2001, a treatment that boosts cancer-killing immune cells. The main outcome that will be measured is how well patients respond to treatment. This study is recruiting in Columbus, OH,...
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