In a nutshell This trial is aiming to examine the effectiveness of an experimental drug, AMXI-5001, in patients with advanced breast cancer. The main outcomes that are to be measured in this trial are side effects and the response to treatment. This trial is going to be carried out in California, Tennessee, and Florida, the United States. The...
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In a nutshell This trial is being carried out to assess the effectiveness of a port delivery system (PDS) loaded with ranibizumab (Lucentis) in order to prevent further progression of diabetic retinopathy (DR; diabetic eye disease). The main outcome of this trial is to assess the improvement in DR following implantation with a PDS. This trial...
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In a nutshell This trial is aiming to examine the effectiveness of ipatasertib in combination with atezolizumab (Tecentriq) and paclitaxel (Taxol) for the treatment of advanced triple-negative breast cancer (TNBC) that cannot be surgically removed. The main outcomes to be measured in this trial is survival without progression of the disease and...
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In a nutshell This trial is aiming to examine the effectiveness of APG-115 with pembrolizumab (Keytruda) in the treatment of metastatic melanoma. The main outcomes to be measured will be the maximum dose tolerated and the overall response to the drug. This trial is recruiting in multiple locations in the United States. The details...
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In a nutshell This trial is aiming to examine the effectiveness and safety of atezolizumab (Tecentriq) and tiragolumab compared to durvalumab (Imfinzi) in stage III non-small-cell lung cancer (NSCLC) that cannot be surgically removed and has previously been treated with concurrent (at the same time) platinum-based chemoradiation therapy (CRT)....
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In a nutshell This trial is examining the effectiveness of Moses Pulse laser on patients with benign prostate hypertrophy (BPH). The main outcome will be the change in blood loss during and after surgery. This study is being conducted in Tennessee, US. The details BPH is a common disorder that affects older men. It consists of an increase in the size...
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In a nutshell This trial is examining the best dose of speech entrainment therapy (SET) to treat aphasia (speech impairment) in stroke survivors. The main outcome will be the number of verbs per minute before and after treatment. This trial will be conducted in South Carolina and Utah, US. The details A stroke happens when the blood flow to the brain...
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In a nutshell This phase 3 trial will investigate the safety and effectiveness of switching from rituximab (Rituxan/Mabthera) to DRL_RI in patients with rheumatoid arthritis (RA). The main outcome will be the rate of side effects and anti-drug drug antibodies (ADAs). This study is recruiting at several locations in the United...
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In a nutshell This study is being carried out to examine whether KRD including carfilzomib (Kyprolis), lenalidomide (Revlimid), and dexamethasone (Decadron) with or without daratumumab (Darzalex) is safe and effective in the treatment of multiple myeloma (MM). The main outcome to be measured is the measurable residual...
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In a nutshell This trial is being carried out to assess the effectiveness of atezolizumab (Tecentriq) in combination with cabozantinib (Cabometyx) versus docetaxel (Taxotere) in patients with metastatic non-small cell lung cancer (NSCLC) which has previously been treated with immunotherapy and platinum-based chemotherapy....
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In a nutshell This trial is aiming to investigate the effectiveness of stereotactic body radiotherapy (SBRT) boost for the treatment in patients with high-risk prostate cancer (PCa). The main outcome that will be measured will be the quality of life (QoL) of patients. This study is being carried out in Ontario, Canada. The details PCa is the...
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In a nutshell This trial is examining the effectiveness of low-intensity shockwave therapy (LIST) on patients with erectile dysfunction (ED). The main outcome will be the change in ED after 1 month of treatment. This study is being conducted in Virginia, US. The details ED (or impotence) affects 18 million men in the US. It consists of the inability...
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