In a nutshell This study will investigate the effects of high-pressure oxygen on the transplant of umbilical cord blood stem cells in patients with blood cancers. The main outcome that will be measured is the time it takes for white blood cells to recover after treatment. This trial is recruiting in New York, US. The details Stem cell transplant (SCT)...
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Searching for participants with leukemia and lymphoma to try a new treatment before stem cell transplantation
In a nutshell This study will investigate the effects of high-pressure oxygen on the transplant of umbilical cord blood stem cells in patients with blood cancers. The main outcome that will be measured is the time it takes for white blood cells to recover after treatment. This trial is recruiting in New York, US. The details Stem cell transplant (SCT)...
Read MoreSearching for participants with leukemia and lymphoma to try a new treatment before stem cell transplantation
In a nutshell This study will investigate the effects of high-pressure oxygen on the transplant of umbilical cord blood stem cells in patients with blood cancers. The main outcome that will be measured is the time it takes for white blood cells to recover after treatment. This trial is recruiting in New York, US. The details Stem cell transplant is...
Read MoreSearching for patients with chronic myeloid leukemia to try a new combination of targeted treatments.
In a nutshell This study is searching for patients with chronic myeloid leukemia (CML) to try a new drug ruxolitinib (NSC-752295) with BCR-ABL Tyrosine Kinase Inhibitors. The main outcome that will be measured is the rate of significant reduction of the BCR-ABL marker. This trial is recruiting across the United States. The details BCR-ABL is a protein...
Read MoreLooking for patients with locally advanced rectal cancer to test a chemotherapy treatment
In a nutshell This phase 2 trial is examining the effectiveness of FOLFOX chemotherapy to treat patients with rectal cancer, without surgery and radiation. The main outcome to be measured will be the tumor response to the treatment. This study is being conducted in New York, US. The details This year an estimated 44,180 people will be diagnosed with...
Read MoreSearch for patients with relapsed or unresponsive small cell lung cancer to try a treatment combination
In a nutshell This study wants to find out how well talazoparib (Talzenna) and temozolomide (Temodal) work for treating patients with small cell lung cancer that has come back after or was unresponsive to initial chemotherapy. The main outcome that will be measured is how long the patients go before the cancer grows. The study is...
Read MoreLooking for patients with advanced lung cancer to test a new drug
In a nutshell This phase 1 study will investigate the dose range and effectiveness of an experimental drug, XmAb23104, in the treatment of advanced lung cancer and other solid tumors. The main outcome will be the safety and tolerability of XmAb23104. This trial is recruiting in Georgia, Texas, and Virginia, the United States. The details Advanced...
Read MoreLooking for patients with advanced colorectal cancer to test a new drug
In a nutshell This phase 1 study will investigate the dose range and effectiveness of an experimental drug, XmAb23104, in the treatment of advanced colorectal cancer and other solid tumors. The main outcome will be the safety and tolerability of XmAb23104. This trial is recruiting in Georgia, Texas, and Virginia, the United States. The details...
Read MoreLooking for patients with advanced triple negative breast cancer to test a new drug
In a nutshell This phase 1 study will investigate the dose range and effectiveness of an experimental drug, XmAb23104, in the treatment of advanced breast cancer and other solid tumors. The main outcome will be the safety and tolerability of XmAb23104. This trial is recruiting in Georgia, Texas, and Virginia, the United States. The details...
Read MoreLooking patient with advanced melanoma to test a new drug
In a nutshell This phase 1 study will investigate the dose range and effectiveness of an experimental drug, XmAb23104, in the treatment of advanced melanoma and other solid tumors. The main outcome will be the safety and tolerability of XmAb23104. This trial is recruiting in Georgia, Texas, and Virginia, the United States. The details...
Read MoreSearching for patients with advanced triple negative breast cancer to trial a new treatment into the tumor
In a nutshell This phase 2 study will investigate Tavokinogene Telseplasmid Electroporation (TTE) in combination with pembrolizumab (Keytruda) in advanced or not suitable for surgery triple-negative breast cancer (TNBC). The main outcome will be the objective response rate (ORR). This trial is recruiting in the United States and...
Read MoreSearching for patients with triple negative breast cancer to test durvalumab and olaparib
In a nutshell This phase 2 study will investigate the safety and effectiveness of olaparib (Lynparza) alone or in combination with durvalumab (Infinzi) in advanced triple negative breast cancer (TNBC). The main outcome will be progression-free survival (PFS). This study is recruiting in Durham, North Carolina, US. The details...
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