You’ve just had an x-ray and are discussing the results with your doctor. The air in the office fills with complicated words after you hear “lung cancer” from your physician. You don’t hear anything else. Not hearing or understanding anything else is part of the shock and a normal reaction. But when you can think or when you have...
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Biomarkers, Combination Therapy, and Lung Cancer
KRAS, one gene present in some cancers, was considered “undruggable” for years.[1] Mutated KRAS is an important target for patients with non-small cell lung cancer (NSCLC) because it’s present in 20-25% of cases.[2] Finally, one drug, sotorasib (Lumakras), is approved to treat one mutant form of KRAS gene, KRAS G12C.[3] This mutation appears in...
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