In a nutshell This study compared the effect of esaxerenone (Minnebro) to eplerenone (Inspra) on night-time blood pressure (BP). It found that esaxerenone had a greater effect on night-time BP than eplerenone. Some background Normally, BP is 10-20% lower during the night compared to day-time BP. Night-time...
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In a nutshell This study aimed to see if chlorthalidone is effective at lowering blood pressure in patients with poor kidney function. Some background The function of the kidney is to filter the blood and remove unnecessary molecules into the urine. When kidney function is low there can be too much or too little of these molecules taken...
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In a nutshell This study evaluated whether blood pressure levels change throughout the day. Some background When blood pressure is measured, the value is given as two numbers; for example 120/80 mmHg. The first (or top number) is the pressure inside arteries when the heart is contracting (systolic blood pressure). The bottom number is the...
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In a nutshell This study examined the effect of aliskiren alone and with other antihypertensive drugs on blood pressure lowering and cardiovascular diseases prevention in elderly patients with mild hypertension. Some background Hypertension (high blood pressure) is a major risk factor in the development of cardiovascular...
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In a nutshell This study reviewed recent medical literature on treatments for high blood pressure which can also prevent heart failure. Some background High blood pressure (or hypertension – HTN) is a condition in which the pressure of blood circulating through the blood vessels (the arteries) is higher than normal. High blood pressure can...
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