In a nutshell This study compared the safety and effectiveness of fimasartan (Kanarb) and perindopril (Coversyl Arginine) for the treatment of high blood pressure (BP) in older patients. It found that fimasartan was associated with better BP control compared to perindopril. Some background There are many different...
Read More
In a nutshell This study compared the effect of esaxerenone (Minnebro) to eplerenone (Inspra) on night-time blood pressure (BP). It found that esaxerenone had a greater effect on night-time BP than eplerenone. Some background Normally, BP is 10-20% lower during the night compared to day-time BP. Night-time...
Read More
In a nutshell The study aimed to assess whether eating a vegetarian diet led to a reduction in blood pressure (BP) when compared to eating an omnivorous diet. The study found that eating a vegetarian diet led to a significant decrease in BP when compared to eating an omnivorous diet. Some background Hypertension is another word for high BP....
Read More
In a nutshell This study investigated the effects of drugs to treat hypertension (anti-hypertensives, AHTs) in pregnancy. They found that AHTs may prevent severe hypertension but the effect on other outcomes is unclear. Some background Hypertension or high blood pressure (BP) is a common condition during pregnancy. In most...
Read MoreIn a nutshell This study investigated a fixed-dose combination of amlodipine and valsartan (AML/VAL) for the treatment of hypertension. They found that AML/VAL reduced blood pressure in patients with poor response to VAL alone. Some background Hypertension or high blood pressure (BP) is a common condition. Managing BP levels in patients with...
Read More
In a nutshell This study investigated the effects of the drug combination perindopril and amlodipine (PEAM) on organ damage in patients with hypertension with and without ischemic heart disease (IHD). They found that PEAM was effective in reducing blood pressure and organ damage in these patients. Some background Hypertension or high blood...
Read MoreIn a nutshell This study investigated if olmesartan (Benicar) reduced blood pressure variability over 24 hours. They found that combination therapy with olmesartan improved blood pressure levels and reduced blood pressure variability. Some background Managing hypertension (high blood pressure) involves using either medication or lifestyle...
Read More
In a nutshell This study examined how different diets could be used to lower high blood pressure. They found that the effect on blood pressure from a modified diet replacing carbohydrates with fat was comparable to a low fat diet. Some background The Dietary Approaches to Stop Hypertension (DASH) eating pattern emphasizes fruit and...
Read More
In a nutshell This paper compared the effect of renal denervation to medication alone in patients with resistant high blood pressure. The authors concluded that renal denervation and intensified medical treatment is similar have similar effects on blood pressure. Some background Resistant hypertension is high blood pressure which cannot be...
Read More
In a nutshell This paper reviewed the American Heart Association guildelines for the treatment of hypertension in patients with coronary artery disease. Some background Coronary artery disease (CAD) refers to a build-up of substances in the blood vessels to the heart. This obstructs blood flow and can increase the risk of angina (chest pain) and...
Read More
In a nutshell This study aimed to see if chlorthalidone is effective at lowering blood pressure in patients with poor kidney function. Some background The function of the kidney is to filter the blood and remove unnecessary molecules into the urine. When kidney function is low there can be too much or too little of these molecules taken...
Read More
In a nutshell This study evaluated whether blood pressure levels change throughout the day. Some background When blood pressure is measured, the value is given as two numbers; for example 120/80 mmHg. The first (or top number) is the pressure inside arteries when the heart is contracting (systolic blood pressure). The bottom number is the...
Read More
