In a nutshell This study investigated whether a single blood pressure (BP) pill containing 4 drugs (quadpill) at quarter doses is more effective than the standard dose of a single drug as initial treatment in patients with hypertension. The data showed that a quadpill was safe and more effective in getting BP under control than the standard...
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Are combination pills better for blood pressure control?
In a nutshell This study looked at patients on triple therapy for blood pressure control. It found that taking fewer separate pills was associated with better blood pressure control. Some background Blood pressure (BP) can be difficult to manage in some patients. There are three main types of treatment that act on the body in...
Read MoreSearching for patients with treatment-resistant high-blood pressure to trial an experimental treatment.
In a nutshell This trial is aiming to assess the effectiveness and safety of a new drug (CIN-107) in patients with treatment-resistant hypertension (rHTN). The main outcome that will be measured is the change in blood pressure over a time-frame of 12-weeks. This trial is being carried out in the United States. The details Resistant...
Read MoreLooking for patients with high blood pressure to test a Chinese herbal medicine
In a nutshell This study is examining the effectiveness of a herbal Chinese traditional medicine for high blood pressure. The main outcome to be measured will be the change in blood pressure after 8 weeks. The details Hypertension can damage blood vessels, which can cause other health problems. These include stroke, heart attacks,...
Read MoreDoes exercise improve heart health and reduce mortality even in those with high blood pressure?
In a nutshell This study examined whether physical activity can help lower mortality risk and improve heart health in people with high blood pressure. This study concluded that physical activity reduced mortality risk, including those with high blood pressure. Some background According to the World Health Organization, hypertension (HT) or high...
Read MoreCan a rice bran supplement lower high blood pressure?
In a nutshell This article investigated the safety and effectiveness of a processed rice bran (PRB) supplement in the management of patients with high blood pressure (BP). The authors concluded that daily consumption of a rice bran supplement with PRB can improve mildly high BP. Some background Hypertension is a condition where the BP...
Read MoreLooking for patients with hypertension to trial a surgical treatment
In a nutshell This trial will evaluate the effectiveness and safety of a device to manage hypertension. The main outcomes will be the rate of adverse events (AEs) and blood pressure (BP) changes. This trial is taking place in the United States. The details Hypertension or high blood pressure (BP) is a common and serious condition. Patients with...
Read MoreLooking for patients with hypertension and chronic kidney disease to test a new drug
In a nutshell This phase 2 trial will investigate the safety and effectiveness of KBP-5074 for the treatment of hypertension. The main outcome will be a change in blood pressure after 84 days. The details Hypertension or high blood pressure is a serious condition. It can lead to major cardiac events such as stroke, heart attack or death....
Read MoreLooking for participants to test a telemonitoring blood pressure management system
In a nutshell This clinical trial will evaluate a telemonitoring system for measuring blood pressure (BP) in the management of hypertension. The main outcome will be any hypertension-related side effects such as visits to the hospital, deaths, heart attacks or strokes during the 6-month trial. The study will be recruiting in Jackson,...
Read MoreDoes high blood pressure increase the risk of aortic valve disease?
In a nutshell This study investigated if elevated blood pressure increases the risk of aortic valve disease (AVD). They found that increasing blood pressure was associated with an increased risk of AVD. Some background Aortic valve disease (AVD) is a condition that affects the heart. The aortic valve allows blood to exit the heart without flowing...
Read MoreSearching for participants to test an exercise program for managing hypertension
In a nutshell This trial will examine the effects of resistance exercise on blood pressure and cardiovascular risk in African Americans. The main outcome to be measured will be changes in blood pressure. This trial is being conducted in Chicago, Illinois. The details Managing blood pressure is important for patients with hypertension (high blood...
Read MoreReducing salt intake and using the DASH diet helps lower blood pressure
In a nutshell This study investigated if reducing salt intake and/or using the DASH diet had any effect on blood pressure levels in patients with pre- or stage 1 hypertension. They found that the combination of reducing salt and adhering to the DASH diet reduced blood pressure. Some background Hypertension (high...
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