In a nutshell This study compared three drugs to see which was better at improving blood flow and reducing inflammation after patients with heart disease were given a stent. The results showed that prasugrel (Efient) improved patients’ blood flow more than clopidogrel (Plavix) or ticagrelor (Brilique). Some background Heart disease,...
Read More
In a nutshell This study investigated the safety and effectiveness of low-dose colchicine (Colcrys) after a heart attack. They found that colchicine reduced the risk of ischemic cardiovascular events in these patients. Some background Coronary artery disease (CAD) is caused by reduced blood flow to the heart. Atherosclerosis (ATS)...
Read More
In a nutshell This trial is examining the effectiveness of a new drug-releasing stent, Svelte, for the treatment of coronary heart disease (CAD). The main outcome to be measured will be target lesion failure (heart attack/death due to blockage in the blood vessel that has the stent) 12 months later. This study is being conducted in the...
Read More
In a nutshell The purpose of this study was to investigate the cholesterol levels and the management of high cholesterol in patients with acute coronary syndrome (heart attack/angina). Patients who had a STEMI (a specific type of heart attack) had worse cholesterol levels but had better cholesterol levels after 12 months of statin therapy. Some...
Read More
In a nutshell This study investigated if bisoprolol (Zebeta) is safe and effective for long-term angina treatment. They found that bisoprolol was effective and well-tolerated long-term. Some background Angina is chest pain caused by reduced oxygen supply to the heart. Reduced blood flow to the heart can be caused by blockages in vessels...
Read More
In a nutshell This study investigated if ranolazine (Ranexa) improved angina symptoms and blood flow. They found that ranolazine improved angina symptoms and blood flow in patients with reduced coronary (blood vessels that supply the heart) flow. Some background Angina is the term for chest pain. Chest pain usually arises when the flow of...
Read MoreIn a nutshell This study investigated if the incidence of coronary microvascular dysfunction in patients with ischemic heart disease. They found that microvascular dysfunction is present in patients with angina. Some background Coronary arteries are responsible for supplying the heart with blood and oxygen. Coronary artery disease (CAD) is caused by a...
Read MoreIn a nutshell This paper studied whether a combination of ezetimibe (Zetia) plus statin treatment is beneficial to patients with acute coronary syndrome (disorders caused by reduced blood flow to the heart). Some background Statins are a group of drugs that reduce levels of low-density lipoprotein (LDL) cholesterol (fatty...
Read More
