In a nutshell This study investigated whether ranolazine was an effective and safe treatment for people with type 2 diabetes. Some background Type 2 diabetes (T2D) is characterized by elevated blood glucose (sugar) levels. Treatment involves lowering blood glucose. Patients are advised to aim for an HbA1c (average blood glucose over the past 3...
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In a nutshell This study investigated the blood sugar reduction and sid-effects associated with 4 different drug combinations in type 2 diabetes. Some background Metformin (Glucophage) decreases glucose production. It is often the first choice of treatment for type 2 diabetes. Commonly, other drugs are prescribed to be taken alongside...
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In a nutshell This study examined whether initial treatment with three drugs was more effective than the traditional treatment method of adding medications over time for type 2 diabetes. Some background Type 2 diabetes is a progressive disease. The cells that produce insulin (beta cells) begin to fail well before the disease is diagnosed, and...
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In a nutshell This study examined whether a combination of empagliflozin (Jardiance) and linagliptin (Tradjenta) was effective as a first-line treatment in patients with type 2 diabetes. Some background Patients with type 2 diabetes either do not make enough or are resistant to insulin, the hormone needed to break down the...
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In a nutshell This study assessed the efficacy and safety of linagliptin (Tradjenta) for the treatment of patients with uncontrolled type 2 diabetes mellitus (T2DM). Some background Patients with T2DM have high blood glucose levels (hyperglycemia) caused by insulin resistance (the cells of the body fail to respond to the normal actions of the...
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In a nutshell This study is a phase 2 clinical trial that tested the safety and efficacy of the oral anti-diabetic drug (OAD) imeglimin in combination with metformin for patients with type 2 diabetes mellitus (T2DM). The results showed that the addition of imeglimin to metformin therapy improved the blood sugar (glucose) control in these patients....
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In a nutshell This study compared the outcomes of metformin (Glucophage) versus insulin treatment in the management of gestational diabetes mellitus (GDM). The authors showed that metformin was a safe and effective alternative to insulin treatment in women with GDM. Some background GDM is a type of diabetes defined by an increase in blood sugar...
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