In a nutshell This research evaluated the effect of dapagliflozin on weight loss in patients with type 2 diabetes mellitus (T2DM) uncontrolled with metformin therapy. The results showed that dapagliflozin reduced blood sugar levels by reducing patients’ weight and increasing the elimination of glucose in urine. Some background T2DM is a...
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Evaluating the efficacy and safety of alogliptin in combination with pioglitazone in patients with type 2 diabetes mellitus uncontrolled with metformin
In a nutshell This study tested the efficacy of the drug combination containing alogliptin and pioglitazone in patients with type 2 diabetes mellitus (T2DM) uncontrolled with high doses of metformin. The results showed that the combination of the two drugs was able to better control blood glucose levels than metformin alone. Some background In...
Read MoreComparing the effecacy and safety of insulin degludec and sitagliptin in patients with type 2 diabetes mellitus uncontrolled with oral anti-diabetic drugs
In a nutshell This study compared the efficacy of insulin degludec (IDeg) to sitagliptin in patients with type 2 diabetes mellitus (T2DM) uncontrolled with oral anti-diabetic drugs (OAD). The results of this study showed that patients treated with IDeg had a better glycaemic (blood sugar) control than those treated with sitagliptin. Some...
Read MoreLong acting insulin versus sitagliptin (Januvia) in type 2 diabetes not controlled with metformin (Glucophage) alone
In a nutshell This study compared the safety and efficacy of Insulin glargine (Lantus) versus Sitagliptin (Januvia) in the management of type 2 diabetes mellitus (T2DM) poorly controlled by Metformin (Glucophage) alone. Main findings: insulin glargine provides better glycemic control than Sitagliptin when added to Metformin therapy. Some...
Read MoreEfficacy and Safety of Dapagliflozin (Forxiga) in Type 2 Diabetics Treated with High Doses of Insulin
In a nutshell This trial assessed the efficacy and safety of a new diabetes drug, Dapagliflozin (Forxiga). Results revealed that the drug helps control difficult cases of type 2 diabetes with only moderate side-effects. Some background Dapagliflozin is a drug recently approved by the European Medicines Agency for the treatment of diabetes. Its...
Read MoreThe impact of three educational strategies on poorly controlled diabetes: An intervention trial
In a nutshell The present study compared the effectiveness of 3 educational strategies aimed at helping patients with uncontrolled diabetes (type 1 and type 2) to achieve glycemic control (good control of blood sugar). All 3 strategies had beneficial effects on glycemic control. Most effective was an intervention based on behavioral group...
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