In a nutshell This study compared the effectiveness and safety of treatment with IDegLira, to treatment with either insulin degludec or liraglutide in type 2 diabetes. Some background Metformin (Glucophage) is typically the first treatment for type 2 diabetes. Commonly, additional drugs are eventually...
Read MoreAnti-diabetes medication(s)-Non-insulin injected drugs Posts on Medivizor
Using canagliflozin in type 2 diabetics with kidney disease
In a nutshell This study investigated whether canagliflozin (Invokana) is safe and effective in type 2 diabetics with kidney disease. Some background Chronic high blood glucose (sugar) levels in patients with type 2 diabetes (T2D) can result in many complications. Kidney disease is one such complication which ultimately results in kidney...
Read MoreType 2 Diabetes – How do different therapy combinations affect cardiovascular health?
In a nutshell This study investigated the effect of 3 different therapy combinations on the occurrence of cardiovascular disease in type 2 diabetes. Some background There are a number of types of drugs that can be used to treat diabetes. Metformin (Glucophage) decreases glucose production, and is often the first choice of treatment...
Read MoreIs weight loss in type 2 diabetes associated with increased bone loss?
In a nutshell This study examined whether an intense lifestyle intervention in type 2 diabetic patients was associated with increased bone loss. Some background Obesity can contribute to type 2 diabetes (T2D) and T2D patients are advised to make lifestyle changes in order to lose weight as weight loss has been shown to reverse or slow progression...
Read MoreThree’s company: Albiglutide is an effective third add-on to metformin therapy
In a nutshell The current study examined the safety and efficacy of albiglutide (Tanzeum) when used in combination with metformin (Glucophage) and glimepiride (Amaryl) in type 2 diabetes. Some background Type 2 diabetes is a progressive disease. While blood glucose (sugar) levels may initially be controlled by diet...
Read MoreA real-life comparison of 3 non-insulin drugs for diabetes
In a nutshell The authors aimed to compare the effects of liraglutide (Victoza) to sitagliptin (Januvia) and exenatide (Byetta) in a real-life setting. Some background Glucagon-like peptide 1 (GLP-1) receptor agonists (liraglutide and exenatide) are drugs used in type 2 diabetes that increase insulin secretion to result in improved blood...
Read MoreLobeglitazone: A novel antidiabetic drug
In a nutshell This study analyzed the glucose-lowering effects of lobeglitazone, a novel antidiabetic drug. Some background Thiazolidinediones are a group of drugs used for improving insulin sensitivity and reducing the production of glucose in the liver in type 2 diabetes. These drugs initiate a response at the peroxisome...
Read MoreDoes insulin glargine result in higher treatment satisfaction than alternative therapies?
In a nutshell The authors aimed to assess patient-reported outcomes associated with initiating insulin glargine among insulin-naïve patients with type 2 diabetes mellitus. Some background While type 2 diabetes may initially be managed with diet, exercise and oral antidiabetic drugs, many patients will need to move to insulin therapy to...
Read MoreCan long term exenatide treatment improve beta-cell function?
In a nutshell This study evaluated the effect of chronic exenatide treatment on beta-cell function and insulin sensitivity in type 2 diabetes. Some background Management of type 2 diabetes is based on a combination of diet, exercise and oral medications focused on keeping blood sugar (glucose) levels as close to normal as possible. However, as...
Read MoreCan liraglutide aid weight loss in type 2 diabetes?
In a nutshell This study investigated the effects of liraglutide (Victoza), a glucagon like peptide 1 (GLP-1) analogue, on appetite and energy intake in patients with type 2 diabetes mellitus. Some background Type 2 diabetes mellitus is a condition in which patients have high blood glucose levels (hyperglycemia) due...
Read MorePredicting the risk of insulin-based hypoglycemia in type 2 diabetes mellitus
In a nutshell This study aimed at predicting which diabetic patients are at risk for developing hypoglycemia with insulin therapy. Some background Patients with type 2 diabetes mellitus (T2DM) cannot regulate their blood glucose levels, leading to a build-up of glucose in the bloodstream. Lifestyle changes, such as diet and exercise, along with...
Read MoreThe impact of three educational strategies on poorly controlled diabetes: An intervention trial
In a nutshell The present study compared the effectiveness of 3 educational strategies aimed at helping patients with uncontrolled diabetes (type 1 and type 2) to achieve glycemic control (good control of blood sugar). All 3 strategies had beneficial effects on glycemic control. Most effective was an intervention based on behavioral group...
Read More
