In a nutshell This study examined whether insulin- calculating smartphone applications are accurate for diabetic patients. Some background Smart phone apps are very useful in healthcare for managing one’s health. Apps which recommend an insulin dose are available for diabetic patients. These apps require patients to enter in their...
Read MoreIn a nutshell This study compared the accuracy of two continuous glucose monitoring systems for type 1 diabetes. Some background Patients with type 1 diabetes do not produce insulin (the hormone needed to break down glucose). Treatment involves replacing the insulin, either through injections or with an insulin pump (a machine that...
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In a nutshell This study compared insulin detemir (Levemir) and insulin NPH (Novolin N, Novolin NPH, Humulin N) for the treatment of pregnant women with gestational or type 2 diabetes. Some background Type 2 diabetes and gestational diabetes are managed similarly in pregnant women. Insulin tends to be the first...
Read MoreIn a nutshell This study examined whether empagliflozin (Jardiance) is safe and effective in type 1 diabetics taking insulin. Some background Patients with type 1 diabetes (T1D) require daily insulin, a hormone which decreases blood glucose (sugar) levels. A drug called empagliflozin is taken orally and decreases blood glucose levels by...
Read MoreIn a nutshell This study compared the safety and effectiveness of lixisenatide (Lyxumi) and liraglutide (Victoza) in type 2 diabetes. Some background Lifestyle changes, such as changes to diet and exercise, and oral antidiabetic medications are first-line treatments for in type 2 diabetes (T2D). Sometimes, these are not enough...
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In a nutshell This study examined the outcomes of a pancreas-kidney transplant and an islet-kidney transplant in type 1 diabetics. Some background In patients with type 1 diabetes (T1D) the immune system attacks the pancreas. The pancreas then fails to produce insulin. Patients therefore require insulin replacement therapy. A pancreas...
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In a nutshell This study examined the number of insulin-treated patients who experience hypoglycemia and the predictive factors for hypoglycemia. Some background Hypoglycemia occurs when the blood glucose (sugar) levels drop below 3.9 mmol/L. In patients with diabetes, insulin use can cause low blood glucose levels. Patients with type 1 diabetes...
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In a nutshell This study investigated whether canagliflozin (Invokana) is safe and effective in type 2 diabetics with kidney disease. Some background Chronic high blood glucose (sugar) levels in patients with type 2 diabetes (T2D) can result in many complications. Kidney disease is one such complication which ultimately results in kidney...
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In a nutshell This trial examined whether suspending insulin release from the insulin pump based on predicting blood glucose levels could prevent low blood glucose levels at night. Some background An insulin pump allows patients with type 1 diabetes (T1D) to enter in the carbohydrate content of a meal and the pump releases insulin based on this. A...
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In a nutshell This trial aimed to determine the safety and effectiveness of an artificial pancreas in young type 1 diabetics living at home. Some background An insulin pump allows patients with type 1 diabetes (T1D) to enter in the carbohydrate content of a meal and the pump releases insulin based on this. A continuous glucose monitor (CGM) is a...
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In a nutshell This study examined whether Ly 2963016 insulin glargine is safe and effective in type 1 diabetics. Some background Insulin glargine (Lantus) is a long-acting insulin which diabetics inject once daily. It is responsible for lowering blood glucose (sugar) levels over a 24 hour period. Insulin glargine (IGlar) was first developed in...
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In a nutshell This study examined the experiences which type 1 diabetics and their caregivers have with continuous glucose (sugar) monitoring. Some background A continuous glucose monitor (CGM) is a device worn by patients with type 1 diabetes (T1D). It allows patients to view their blood glucose levels in real-time (every few minutes). This...
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