In a nutshell This study investigated the safety and effectiveness of anti-hypertensive (AHT) drugs in pregnancy. They found that AHTs were generally safe in pregnancy. Some background Hypertension or high blood pressure (BP) is present in 3-5% of pregnancies. Uncontrolled BP can have negative effects on the mother and baby. Hypertension is...
Read MoreProstatic urethral lift improves the outcomes of patients with benign prostatic hyperplasia
In a nutshell This study investigated the effectiveness of prostatic urethral lift (PUL) in the treatment of benign prostatic hyperplasia (BPH). Researchers suggested that this treatment is a good and safe option to treat BPH. Some background BHP consists of the enlargement of the prostate gland. This may compress the urethra (urinary tube) causing...
Read MoreHow effective are bioresorbable scaffolds to treat patients with coronary artery disease?
In a nutshell This study examined how effective bioresorbable scaffolds (BRS) were at preventing heart complications in patients with coronary artery disease (CAD). The study found that while BRS were somewhat effective, some patients still developed complications. Some background CAD is caused by the narrowing of blood vessels in the heart....
Read More10 year outcomes of early-stage Hodgkin lymphoma
In a nutshell This study looked at long-term outcomes of patients with early-stage Hodgkin lymphoma according to different treatments. It found that patients who received both radiation and chemotherapy had improved long-term survival compared to either treatment alone. Some background At present, over 90% of patients with classical Hodgkin lymphoma...
Read MoreHow effective and safe is high-dose chemotherapy and stem cell transplant for children with lymphoma?
In a nutshell This study examined the effectiveness and safety of high-dose chemotherapy and stem cell transplants for children with lymphoma. The study showed that the combination treatment was very effective but that the dose may need to be adjusted for some patients. Some background Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) have very...
Read MoreHow effective and safe is high-dose chemotherapy and stem cell transplant for children with lymphoma?
In a nutshell This study examined the effectiveness and safety of high-dose chemotherapy and stem cell transplants for children with lymphoma. The study showed that the combination treatment was very effective but that the dose may need to be adjusted for some patients. Some background Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL)...
Read MoreManaging joint and muscle pain in patients with chronic lymphocytic leukemia treated with ibrutinib
In a nutshell The study evaluated the occurrence and risks of joint/muscle pain as side effects of ibrutinib (Imbruvica) in patients with chronic lymphocytic leukemia (CLL). The authors found that 36% of patients developed joint/muscle pain and most were younger and females receiving ibrutinib as the first treatment. Some background Ibrutinib kills...
Read MoreEvaluating lurbinectedin for unresponsive small cell lung cancer
In a nutshell This study evaluated the safety and effectiveness of an experimental treatment, lurbinectedin, in patients with small-cell lung cancer (SCLC) after unsuccessful treatment with platinum-based chemotherapy. The authors found that this treatment showed promising effectiveness and manageable side effects in these...
Read MoreLong-term nilotinib treatment for newly diagnosed chronic-phase chronic myeloid leukemia
In a nutshell This study aimed to investigate if nilotinib was safe and effective as a long-term treatment in patients with chronic-phase chronic myeloid leukemia. This study concluded that nilotinib is safe and effective in the long-term in these patients. Some background Nilotinib...
Read MoreDoes the frequency of radiotherapy doses impact its effectiveness and safety for patients with localized prostate cancer?
In a nutshell This study examined if the frequency of the same dose of radiotherapy (RT) changed the effectiveness and safety of patients with localized prostate cancer (PC). The results showed that RT that was given weekly was as effective and safe as RT given every other day. Some background Radiotherapy (RT) is an effective treatment for...
Read MoreIbrutinib for first-line and relapsed/refractory chronic lymphocytic leukemia: long-term outcomes
In a nutshell This study aimed to investigate the long-term safety and effectiveness of ibrutinib in patients with chronic lymphocytic leukemia or small lymphocytic lymphoma. This study concluded that ibrutinib was safe and effective in the long-term in this group. Some background Ibrutinib (Imbruvica) is a...
Read MoreLong-term outcomes for acute myeloid leukemia patients treated with reduced intensity conditioning and hematopoietic stem cell transplant
In a nutshell This study aimed to investigate the long-term outcomes for patients with acute myeloid leukemia who received reduced-intensity conditioning and allogeneic stem cell transplant. This study concluded that this treatment is safe and effective in these patients in the long-term. Some background One of the standard...
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