In a nutshell This study aimed to investigate second treatments in patients with chronic myeloid leukemia (CML) who had been initially treated with second-generation tyrosine kinase inhibitors (TKI). This study concluded that switching from second-generation TKIs in these patients was relatively uncommon. Some background...
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In a nutshell The report recommends several treatment modifications for patients with leukemia during the high-risk period of the COVID-19 pandemic. The main recommendations are to reduce clinic visits, use less intensive chemotherapy, and care through telemedicine for effective treatment. Some background Managing patients with leukemia during...
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In a nutshell This study investigated if reducing the doses (tapering) of biologic drugs maintains effectiveness in patients with rheumatoid arthritis (RA). They found that drug tapering maintained low disease activity (LDA) and remission while reducing side effects and costs. Some background Rheumatoid arthritis (RA) is a chronic...
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In a nutshell This study investigated the benefits of repeated cytoreductive surgery (CRS) and hyperthermic peritoneal chemotherapy (HIPEC) in patients with advanced colorectal cancer. Researchers suggested that repeated treatment improves the survival of patients with advanced colorectal cancer, without an increase in side effects. Some background...
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In a nutshell This study aimed to investigate kidney function in patients with chronic-phase (CP) chronic myeloid leukemia (CML) before and after tyrosine kinase inhibitor (TKI) treatment. This study concluded that long-term TKI treatment leads to kidney side effects in these patients that may be irreversible after stopping...
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In a nutshell This study examined older patients with Hodgkin lymphoma (HL) to understand how other serious health conditions affect their diagnosis and treatment. The authors found that patients with more serious illnesses were more likely to be diagnosed with advanced HL and had limited treatment options. Some background Treatment options for...
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In a nutshell This study compared two doses of dapagliflozin (Farxiga) to a placebo to determine how effective and safe they were long-term for patients with uncontrolled type 1 diabetes (T1D). The results showed that both doses were able to reduce blood glucose levels and body weight but increased the risk of ketoacidosis. Some background...
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In a nutshell This study compared the effectiveness and safety of bevacizumab biosimilar (BE1040V) to the reference drug (Avastin) in the treatment of patients with metastatic colorectal cancer (mCRC). Researchers suggested that the effectiveness and safety of the biosimilar were similar to the reference drug bevacizumab. Some...
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In a nutshell This study looked at exenatide (Byetta) for patients with type 2 diabetes (T2D) and kidney damage. It found that exenatide may reduce kidney damage compared to other diabetes treatments. Some background T2D is a disorder in which the body does not respond well to the hormone insulin. This causes high levels of glucose (sugar) in the...
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In a nutshell This study compared ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) and brentuximab vedotin (Adcedris; A) + AVD (doxorubicin, vinblastine, and dacarbazine) chemotherapy combinations to understand which is more effective long term for patients with advanced classical Hodgkin lymphoma (HL). The authors concluded...
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In a nutshell This study examined the effectiveness of a modified anti-nausea and vomiting treatment for patients with aggressive non-Hodgkin lymphoma (NHL) receiving high-dose (HD) chemotherapy. The results showed that netupitant/palonosetron (NEPA; Akynzeo) alone was very effective and safe for these patients. Some background Chemotherapy...
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In a nutshell This study looked at stress and cortisol levels in couples using in vitro fertilization (IVF) and other reproductive technologies. It found that women who became pregnant had higher cortisol levels, while the stress and cortisol levels of male partners were not related to pregnancy. Some background Infertility can be a long and stressful...
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