In a nutshell This study aimed to investigate the impact of a pharmaceutical care program on the safety and effectiveness of ibrutinib in patients with B-cell non-Hodgkin's lymphoma (NHL). This study concluded that the management of ibrutinib treatment by using a pharmaceutical care program results in improved survival and better tolerance than...
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In a nutshell This study aimed to investigate the impact of a pharmaceutical care program on the safety and effectiveness of ibrutinib in patients with chronic lymphocytic leukemia. This study concluded that management of ibrutinib treatment by using a pharmaceutical care program results in improved survival and better...
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In a nutshell This study investigated if subcutaneous methotrexate (MTX-sc; Otrexup) is safe and well tolerated in patients with rheumatoid arthritis (RA). They found that MTX-sc is safe and well-tolerated in these patients. Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by painful inflammation in...
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In a nutshell This study investigated the effectiveness and safety of prolonged-release melatonin (PRM; Circadin) in patients with Parkinson's disease (PD) and poor sleep quality. Researchers suggested that PRM is a good and safe option do treat these patients. Some background Parkinson's disease (PD) is a chronic disorder that affects 60,000...
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In a nutshell This study looked at how gastric bypass weight-loss surgery affects kidney function for patients with type 2 diabetes, obesity, and early kidney disease. It found that weight-loss surgery improved kidney function more than standard medical care in these patients. Some background Patients with type 2 diabetes (T2D) are at increased risk...
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In a nutshell This study compared two different chemotherapy treatments in metastatic colorectal cancer (mCRC; spread to other parts of the body). Researchers suggested that 24-hour infused irinotecan (Camptosar) plus oral S-1 (Teysuno) chemotherapy and bevacizumab (Avastin) is well tolerated and associated with improved outcomes. Some background...
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In a nutshell This article outlined the current guidelines for treatment for patients with classical Hodgkin lymphoma (cHL). Some background Treatments for patients with cHL have advanced in the last number of years and most patients can be cured. Treatment options include chemotherapy (CT), radiotherapy (RT), and biological...
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In a nutshell This study investigated treatment tapering strategies (TTS) in patients with rheumatoid arthritis (RA). They found that drug-free remission (DFR) can be achieved in a small number of patients. Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by excessive inflammation. This leads to painful swelling in...
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In a nutshell This study reviewed the effectiveness and safety of vibegron in the treatment of overactive bladder (OAB). Researchers suggested that vibegron was associated with improved OAB symptoms and was well tolerated. Some background OAB consists of a frequent and sudden urge to urinate that may be difficult to control. It is present in 18.6% of...
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In a nutshell The study assessed whether pembrolizumab (Keytruda) could be used in addition to neoadjuvant chemotherapy (NAC; chemotherapy before surgery) to improve the outcomes of patients with early triple-negative breast cancer (TNBC). The study found that more patients treated with pembrolizumab had a complete response. Some...
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In a nutshell This study assessed whether olaparib (Lynparza) affected progression-free survival (PFS; survival without cancer worsening) in patients with metastatic castration-resistant prostate cancer (mCRPC) and certain genetic mutations (abnormalities). The study found that olaparib improved PFS in these patients. Some...
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In a nutshell This study aimed to compare two salvage regimes for patients with relapsed/refractory acute myeloid leukemia. This study concluded that both regimens have similar effectiveness in terms of overall response but one shows a significant reduction in side effects in these patients. Some background...
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