In a nutshell This study investigated if sarilumab (Kevzara) is safe and effective alone or in combination with other drugs in patients with moderate to severe rheumatoid arthritis (RA). They found that this treatment was effective and well-tolerated in these patients. Some background Rheumatoid arthritis (RA) is a chronic immune...
Read More
In a nutshell This study investigated the long-term durability and effectiveness of the adjustable transobturator male system (ATOMS) in patients with urinary incontinence. Researchers suggested that ATOMS is a good and safe option to treat these patients long-term. Some background Stress urinary incontinence is a common side effect after prostate...
Read More
In a nutshell This study assessed whether patients with metastatic non-small-cell lung cancer (mNSCLC) would benefit from treatment using durvalumab (Imfinzi) with or without tremelimumab (CP-675,206) as a later treatment. The authors concluded that durvalumab showed improvement in overall survival (OS) and...
Read More
In a nutshell The study evaluated whether the combination of atezolizumab (Tecentriq), vemurafenib (Zelboraf), and cobimetinib (Cotellic) or AVC can effectively treat patients with BRAFV600 mutation-positive advanced melanoma (AM). The authors found that this combination was safe and effective as an initial treatment in such...
Read More
In a nutshell This study aimed to investigate the safety and effectiveness of the combination of all-trans-retinoic acid (Vesanoid), arsenic trioxide (Trisenox), and idarubicin (Idamycin) as front-line treatment for acute promyelocytic leukemia. This study concluded that this combination is safe and effective for these...
Read More
In a nutshell This study aimed to compare the safety and effectiveness of bendamustine–rituximab (BR) and chlorambucil–rituximab (Chl-R) as a front-line treatment in older patients with chronic lymphocytic leukemia (CLL). This study concluded that both treatments are good options for these...
Read More
In a nutshell This study investigated the effectiveness and safety of vibegron in the treatment of overactive bladder (OAB). Researchers suggested that this drug is a good and safe option for the treatment of OAB. Some background Around 17% of adults experience OAB in Europe and the USA. OAB consists of frequent and sudden urge to urinate that is...
Read More
In a nutshell This study investigated the effectiveness of cetuximab (Erbitux) in combination with chemotherapy for the treatment of advanced colorectal cancer (CRC). Researchers suggested that this combined treatment improves the outcomes of patients with CRC. Some background CRC is one of the most common cancers worldwide. Around 15 to 25% of...
Read More
In a nutshell This study compared the risk of severe hypoglycemia (dangerously low blood glucose levels) with insulin glargine-100 (Lantus) and insulin glargine-300 (Toujeo) for patients with type 1 diabetes (T1D). It found that both medications improved glucose control, and insulin glargine-300 had a lower risk of hypoglycemia. Some background T1D is...
Read More
In a nutshell This review analysis looked at whether psyllium fiber supplements benefit patients with type 2 diabetes (T2D). It found that psyllium improves LDL cholesterol and blood sugar control for patients with T2D. Some background Diabetes is a metabolic condition in which the body cannot reduce high levels of glucose (sugar) in the blood....
Read More
In a nutshell This study aimed to investigate the safety and effectiveness of combining daunorubicin (Cerubidine) and cytarabine (Cytosar-U) compared to idarubicin (Idamycin) and cytarabine as induction treatment for patients with acute myeloid leukemia. This study concluded that the idarubicin and cytarabine combination...
Read More
In a nutshell The study evaluated if brentuximab-vedotin (BV; Adcetris) consolidation therapy can reduce the use of radiation therapy (RT) in patients with limited-stage (LS) Hodgkin lymphoma (HL). The authors found that BV consolidation achieved good outcomes in such patients when given after ABVD therapy. Some background HL is a cancer of the...
Read More
