In a nutshell This study reviewed the outcomes of onabotulinumtoxinA (BTX) and sacral neuromodulation (SNM) in the treatment of overactive bladder (OAB). Researchers suggested that both treatments improved the outcomes of these patients, but BTX may be associated with more complications. Some background OAB of an uncontrolled need to urinate...
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In a nutshell This study reviewed the effectiveness of water vapor thermal therapy (WVTT) as a treatment for urinary symptoms related to benign prostatic hyperplasia (BPH). Researchers suggested that this therapy improves the outcomes of these patients. Some background BPH consists of the enlargement of the prostate gland and is a common condition in...
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In a nutshell This study compared the survival outcomes of different chemotherapy treatments in patients with inoperable advanced colorectal cancer (CRC). Researchers suggested that FOLFOXIRI plus bevacizumab (Avastin) significantly improved the survival of these patients. Some background Around 20% of patients present with advanced CRC at diagnosis....
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In a nutshell This study aimed to investigate if the combination of dasatinib and decitabine was safe and effective in patients with advanced chronic myeloid leukemia. This study concluded that this treatment is safe and effective in these patients. Some background Treatment of advanced-phase chronic myeloid...
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In a nutshell This trial was carried out to look at how safe and effective the addition of daratumumab (Darzalex) would be to the RVd regimen involving lenalidomide (Revlimid), bortezomib (Velcade), and dexamethasone (Decadron) in the treatment of patients with newly diagnosed multiple myeloma (MM). The...
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In a nutshell This trial was carried out to examine the effectiveness and safety profile of pembrolizumab (Keytruda) and nivolumab (Opdivo) for the treatment of classical Hodgkin lymphoma (cHL) that has relapsed and is refractory (resistant to drug treatment). The authors found that...
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In a nutshell This study examined the role of statin (cholesterol-lowering) therapy in lowering the risk of diabetic eye disease and sight-threatening complications of diabetes. They found that patients taking a statins were less likely to suffer from advanced diabetic eye disease than those not taking a statin. Some background...
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In a nutshell This study aimed to investigate the safety and effectiveness of the combination of obinutuzumab (Gazyva), ibrutinib (Imbruvica) and venetoclax (Venclexta) in patients with chronic lymphocytic leukemia. This study concluded that this treatment is safe and effective for these patients. Some...
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In a nutshell This overview discusses initial treatment options for classical Hodgkin lymphoma (cHL). Some background Classical HL is a cancer of the lymph nodes. Early-stage (stage I/II) cHL is contained to half the body, while advanced (stage III/IV) has spread to both the upper and lower halves of the body. Both early and advanced cHL have...
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In a nutshell This study aimed to investigate if postinduction central nervous system (CNS; brain and spine) protection with intrathecal (injection into the spine) triple therapy (ITT) would improve the outcomes for pediatric patients with acute lymphoblastic leukemia (ALL) when compared to intrathecal methotrexate (MTX; Otrexup)...
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In a nutshell This study analyzed the risk of infections for patients with rheumatoid arthritis (RA) treated with baricitinib (Olumiant). The study showed that there is a higher risk of non-serious infections in patients taking baricitinib. Some background RA is a chronic inflammatory auto-immune disease affecting the whole...
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In a nutshell This study investigated the effects of bevacizumab (Avastin) combined with mFOLFOX6 (fluorouracil, leucovorin, and oxaliplatin) treatment in RAS-positive advanced colorectal cancer (CRC). Researchers suggested that this treatment improved the treatment and survival outcomes of patients with CRC and liver metastasis (spread to the...
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