In a nutshell The study evaluated the safety and effectiveness of 177Lu-lilotomab satetraxetan (177LLS; Betalutin) in patients with relapsed/refractory (r/r) indolent non-Hodgkin lymphoma (iNHL). The main finding was that 177LLS was proven to be a valuable alternative treatment in such patients. Some background NHL is a type of lymphoma that spreads...
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In a nutshell This study investigated the effectiveness and safety of transperineal interstitial laser ablation (TILA) in the treatment of benign prostatic obstruction (BPO). Researchers suggested that TILA shows good effectiveness and safety outcomes. Some background BPO is present in about half the men between the ages of 51 and 60. It happens...
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In a nutshell This study aimed to investigate the safety and effectiveness of flumatinib (HHGV678) compared to imatinib (Gleevec) in patients with chronic-phase chronic myeloid leukemia. This study concluded that flumatinib was a safe and more effective than imatinib in these patients. Some background...
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In a nutshell This trial was carried out to examine the effectiveness of radiotherapy followed by treatment with ipilimumab (Yervoy) in men with metastatic castrate-resistant prostate cancer (mCRPC). The trial found that this treatment led to higher survival in these patients compared to radiotherapy followed by placebo. Some...
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In a nutshell This analysis was carried out to look at including regorafenib (Stivarga) in second-line therapy for patients with metastatic colorectal cancer (mCRC). The authors found that regorafenib in combination with chemotherapy might be an alternative to standard second-line treatment options for these patients. Some...
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In a nutshell This trial was carried out to examine the use of recombinant human (rh) endostatin (EN) with CT before surgery in patients with breast cancer (BC). The authors concluded that the addition of EN to CT significantly improved the response rate to therapy and survival in these patients. Some background BC is the most common form of...
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In a nutshell This study compared the effectiveness of transurethral prostate resection (TURP) and thulium laser vaporesection (TLV) in patients with benign prostate obstruction (BPO). Researchers suggested that both methods have similar effectiveness in these patients. Some background Benign prostate obstruction (BPO) is caused by prostate...
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In a nutshell This study was conducted to assess the safety and patient reported outcomes (PRO) of the addition of atezolizumab (Tecentriq) to chemotherapy with and without bevacizumab (Avastin) vs bevacizumab plus chemotherapy in the treatment of nonsquamous non-small cell lung cancer (NSCLC). The addition...
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In a nutshell This study reviewed if antioxidant supplementation (AOS) improves fertility outcomes. They found that AOS was not associated with better fertility outcomes. Some background Infertility is a common condition. It is diagnosed if a couple has not conceived within one year of regular intercourse. Subfertility (SF) is when a couple...
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In a nutshell This trial was carried out to assess the effectiveness of azacitidine (Vidaza) in combination with venetoclax (Venclexta) for the treatment of untreated acute myeloid leukemia (AML) in older adults. The authors concluded that this combination prolonged survival and induced more remissions in these patients. Some...
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In a nutshell This study evaluated the survival rate of patients with prostate cancer (PC) that no longer responded do hormonal therapy (castration resistant) being treated with darolutamide (Nubeqa). The study found that darolutamide may improve survival rates and delay the start of heavy chemotherapy in these...
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In a nutshell This study aimed to investigate the safety and effectiveness of nelarabine (Arranon) in young patients with newly diagnosed T cell acute lymphoblastic leukemia. This study concluded that nelarabine improves disease-free survival for these patients without increasing toxicity. Some background A...
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