In a nutshell This study investigated the effectiveness and safety of sacral neuromodulation (SNM) with the InterStim system in the treatment of lower urinary symptoms such as urinary incontinence (UI) in real-world medical practice. Researchers suggested that this treatment is associated with improved effectiveness and quality of life in these...
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In a nutshell This study investigated the effectiveness and safety of sacral neuromodulation (SNM) with the InterStim system in the treatment of overactive bladder (OAB) in real-world practice. Researchers suggested that this treatment is associated with improved effectiveness and quality of life in these patients. Some background Overactive bladder...
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In a nutshell This study investigated the effectiveness and impact on patient satisfaction of mirabegron (Myrbetriq) in patients with overactive bladder (OAB). Researchers suggested that this drug improved the treatment satisfaction of patients with OAB. Some background OAB consists of an uncontrollable need to urinate with or without incontinence...
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In a nutshell This study presents updated longer-term data on recurrence-free survival (RFS) for pembrolizumab (Keytruda) after surgery for stage 3 melanoma. The study showed that pembrolizumab has a lasting and improving effect on RFS as a treatment after surgery. Some background For patients with stage 3 melanoma,...
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In a nutshell This study investigated the effectiveness and safety of atezolizumab (Tecentriq) as an addition to chemotherapy before surgery for patients with early-stage triple-negative breast cancer (TNBC). The data showed that the combination is effective in improving treatment response in these patients. Some background...
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In a nutshell This trial is looking to examine the effectiveness of carboplatin (Paraplatin), paclitaxel (Taxol), and ramucirumab (Cyramza) in the treatment of advanced non-squamous non-small cell lung cancer (NSCLC) that is progressive after maintenance therapy. The main outcome that is to be measured is the response of the...
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In a nutshell This study was carried out to assess the safety and effectiveness of a chemotherapy regimen including gemcitabine (Gemzar) and vinorelbine (Navelbine) for relapsed childhood Hodgkin lymphoma (HL). The authors found that this regimen is effective in treating childhood HL in the outpatient setting and there was low...
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In a nutshell This trial was carried out to examine the effectiveness of pembrolizumab (Keytruda) consolidation therapy for patients with stage III unresectable non-small cell lung cancer (NSCLC) following a course of chemotherapy and radiation therapy. The authors found that pembrolizumab consolidation improved the outcomes of...
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In a nutshell This trial was carried out to assess the long-term results of external-beam accelerated partial-breast irradiation (APBI) intensity-modulated radiation therapy (IMRT) compared to whole-breast irradiation (WBI) in early-stage breast cancer (BC). The authors found that the 10-year recurrence of breast tumors was similar between the 2 methods,...
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In a nutshell This study aimed to further investigate the safety and tolerability of midostaurin plus chemotherapy in patients with newly diagnosed FLT3 mutation-positive acute myeloid leukemia. This study concluded that this combination was safe and effective in these patients. Some background FLT3 is a mutation...
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In a nutshell This study investigated Immunoscore (IMS) as a prognostic tool in patients with stage 3 colon cancer. Researchers suggested that a high IMS is associated with prolonged survival in these patients. Some background Colorectal cancer is the third most common cancer worldwide. A significant percentage of patients present with high-risk...
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In a nutshell This trial was carried out to examine the effectiveness and safety of elotuzumab (Empliciti), lenalidomide (Revlimid), and dexamethasone (Decadron) in relapsed or refractory (unresponsive) multiple myeloma (MM). The authors found that there was an improved survival in these patients in the long-term. Some...
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