In a nutshell This study investigated the occurrence of cachexia (CX; weight loss and muscle wasting) in patients with advanced colorectal cancer after first-line therapy. Researchers suggested that CX is present in half of these patients within 24 weeks after starting first-line therapy. Some background Colorectal cancer is the third most common...
Read MoreIs rehabilitation at home after stroke more effective than conventional rehabilitation?
In a nutshell This study compared the effect of a conventional rehabilitation (CR) program to a home-based motor training rehabilitation (TR) program for patients with hemiplegia after stroke. The study showed that TR positively impacts movement function in the upper and lower extremities as well as skills...
Read MoreTazemetostat as treatment for patients with relapsed or refractory follicular lymphoma
In a nutshell This study aimed to investigate if tazemetostat (Tazverik) was a safe and effective treatment in patients with relapsed/refractory follicular lymphoma (FL). This study concluded that tazemetostat provided durable responses and was well tolerated in these patients. Some background Tazemetostat is...
Read MorePlaque incision or excision and grafting of collagen TachoSil improves the outcomes of patients with Peyronie’s disease
In a nutshell This study investigated the effectiveness and safety of plaque incision/excision and or grafting (PIG/PEG) with collagen TachoSil to treat erectile dysfunction in patients with Peyronie's disease (PD). Researchers suggested that PIG/PEG is a good and safe procedure to treat these patients. Some background PD consists of...
Read MoreIrinotecan combined with capecitabine-based chemoradiotherapy before surgery improves the outcomes of patients with rectal cancer
In a nutshell This study investigated the effectiveness of treatment with irinotecan (Camptosar) combined with capecitabine (Xeloda) chemotherapy (ICC) before rectal cancer surgery. Researchers suggested that this combined therapy significantly improved the treatment outcomes in these patients. Some background Rectal cancer is a common...
Read MoreCould venetoclax combined with bortezomib and dexamethasone help to treat patients with relapsed/refractory multiple myeloma?
In a nutshell This study investigated whether giving patients with relapsed/resistant multiple myeloma (MM) venetoclax (Venclexta), in combination with bortezomib (Velcade) and dexamethasone (Ozurdex), will improve patient survival. This study showed that these patients would benefit from this treatment combination. Some background...
Read MoreDoes giving radiotherapy to metastatic sites and the prostate tumor improve the outcomes of patients with prostate cancer and few metastases?
In a nutshell This study aims to evaluate if giving radiotherapy to both the areas the tumor has spread (metastases), along with the prostate tumor, will improve the survival of patients with prostate cancer (PC) and few metastases (oligometastatic disease). This study suggested that this treatment could benefit patients with PC and few...
Read MoreSearching for patients with triple-negative breast cancer to test an immunotherapy combination
In a nutshell This study will investigate the safety and effectiveness of tiragolumab combined with atezolizumab (Tecentriq) and chemotherapy to treat triple-negative breast cancer (TNBC). The main outcome will be the occurrence of side effects and the objective response rate (ORR). The details Breast cancer (BC) is the most...
Read MoreSearching for patients with EGFR-positive advanced tumors to trial an experimental treatment.
In a nutshell This trial is being carried out to assess the safety and effectiveness of an experimental drug called BCA101 alone and in combination with pembrolizumab (Keytruda) in advanced solid tumors that are EGFR-positive. The main outcomes to be measured are the occurrence of side effects and response to treatment. The details Advanced solid...
Read MoreSearching for patients with EGFR-positive advanced tumors to trial an experimental treatment.
In a nutshell This trial is being carried out to assess the safety and effectiveness of an experimental drug called BCA101 alone and in combination with pembrolizumab (Keytruda) in advanced solid tumors that are EGFR-positive. The main outcomes to be measured are the occurrence of side effects and response to treatment. The details Advanced solid...
Read MoreSearching for patients with EGFR-positive advanced tumors to trial an experimental treatment.
In a nutshell This trial is being carried out to assess the safety and effectiveness of an experimental drug called BCA101 alone and in combination with pembrolizumab (Keytruda) in advanced solid tumors that are EGFR-positive. The main outcomes to be measured are the occurrence of side effects and response to treatment. The details Advanced solid...
Read MoreSearching for patients with EGFR-positive advanced tumors to trial an experimental treatment.
In a nutshell This trial is being carried out to assess the safety and effectiveness of an experimental drug called BCA101 alone and in combination with pembrolizumab (Keytruda) in advanced solid tumors that are EGFR-positive. The main outcomes to be measured are the occurrence of side effects and response to treatment. The details Advanced...
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