In a nutshell This study aimed to investigate the safety and effectiveness of venetoclax (Venclexta) combined with low dose cytarabine (LDAC; Cytosar-U) in patients with acute myeloid leukemia (AML) who cannot undergo intensive chemotherapy. This study concluded that this combination is a promising treatment for...
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In a nutshell This study investigated the effectiveness of a drink supplement with testofen, L-citrulline, resveratrol, and caffeine (TLRC) in improving sexual function in men taking phosphodiesterase type 5 inhibitors (PDE5-i). Researchers suggested that the TLRC drink improves the sexual function in these patients. Some background Erectile...
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In a nutshell This study looked at the effectiveness and safety of belotecan (Bel; Camtobell) and topotecan (Top; Hycamtin) as therapy for sensitive relapsed small-cell lung cancer (SCLC). The authors found that Bel could be used as an alternative to Top for sensitive-relapsed SCLC. Some background SCLC...
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In a nutshell This study was carried out to look at the use of a reduced dose of erlotinib (Tarceva) in the treatment of EGFR-mutated advanced non-small cell lung cancer (NSCLC). The authors found that lower-dose erlotinib was as effective as standard dose gefitinib (Iressa) in these patients. Some background NSCLC is the...
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In a nutshell This study aimed to evaluate the safety and effectiveness of loncastuximab tesirine (LoT; Lonca) for the treatment of patients with relapsed/refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL). The study found that LoT was safe and had promising activity in these patients. Some background B-NHL is a type of...
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In a nutshell This study aimed to investigate the effectiveness of inotuzumab ozogamicin (InO; Besponsa) in patients with Philadelphia chromosome-positive (Ph+) relapsed/refractory (r/r) acute lymphoblastic leukemia (ALL). This study concluded that this treatment is a good option for these patients. Some background Ph chromosome...
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In a nutshell The study compared outcomes of utidelone plus capecitabine (Xeloda) versus capecitabine (C) alone in previously treated patients with anthracycline- and taxane-resistant metastatic breast cancer (MBC). The authors found that this combination improved survival compared to C alone in such patients. Some background...
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In a nutshell This study investigated the effectiveness and safety of levodopa inhalation powder (CVT-301; Inbrija) in the treatment of wearing-OFF symptoms in patients with Parkinson's disease (PD). Researchers suggested that CVT-301 decreased the daily OFF time of these patients with manageable side effects. Some background...
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In a nutshell This study compared the effectiveness of giving androgen deprivation therapy (ADT) before or after radiotherapy (RT) for prostate cancer (PCa). The study found that treatment with RT followed by ADT increased patient survival without the spread of the disease. Some background PCa can often spread to other locations within the...
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In a nutshell This study looked at the safety and benefits of starting sotagliflozin (Zynquista) in patients with type 2 diabetes (T2D) who were recently hospitalized for heart failure. They found that patients started on sotagliflozin within 2 days of discharge from the hospital had a lower risk of serious complications including...
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In a nutshell This study looked at the treatment of poorly-controlled type 2 diabetics. They found that a combination of exenatide and dapagliflozin was more effective at lowering blood glucose (sugar) than either treatment alone. Some background There are many types of treatment for type 2 diabetes (T2D). Metformin (Glucophage) is commonly...
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In a nutshell This study compared the use of steroid eye injections with other treatments for diabetic macular edema (DME). They found that steroid injections may improve vision slightly compared to placebo, but are possibly less effective than other types of injection. Steroid injections also increase the risk of cataracts and increased...
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