In a nutshell This study reviewed the research on bladder problems in patients who had radical prostatectomy (RP – complete removal of their prostate). The review found that retention (holding too much urine) and incontinence (unable to hold urine) were common problems in men after RP but can be treated in a number of ways. Some background...
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In a nutshell This study investigated the negative side effects of targeted therapy to treat elderly and younger metastatic (spread to other parts of the body) colorectal cancer patients. Researchers suggested that side effects were different between these patients. Some background Colorectal cancer is one of the most common cancers worldwide....
Read MoreIn a nutshell This study aimed to investigate the incidence of pulmonary hypertension in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors. This study concluded that treating CML patients with tyrosine kinase inhibitors can lead to mild pulmonary hypertension. Some background Tyrosine kinase inhibitors (TKIs) are a...
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In a nutshell In this review, the authors look at the most common adverse events related to ibrutinib and idelalisib, B-cell inhibitors. The study concluded that both ibrutinib and idelalisib are effective at treating B-cell cancers, and the side effects are within a normal range compared to other similar treatments. Some background Ibrutinib and...
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In a nutshell In this review, the authors look at the most common adverse events related to ibrutinib and idelalisib, B-cell inhibitors. The study concluded that both ibrutinib and idelalisib are effective at treating B-cell cancers, and the side effects are within a normal range compared to other similar treatments. Some...
Read MoreIn a nutshell This meta-analysis aimed to establish the incidence of severe and fatal side effects associated with crizotinib (Xalkori) in patients with ALK-positive non-small-cell lung cancer (NSCLC). The authors concluded that crizotinib does not increase the risk of severe or fatal side effects compared to chemotherapy. Some background The...
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In a nutshell This study aimed to investigate the adverse events of inotuzumab ozogamicin (Besponsa) for treatment of relapsed or refractory acute lymphoblastic leukaemia. This study concluded that inotuzumab ozogamicin leads to increased liver damage when compared to standard therapy. Some background Acute lymphoblastic leukaemia (ALL) occurs...
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In a nutshell This study aimed to investigate atrial fibrillation as a side effect of ibrutinib (imbruvica) in chronic lymphocytic leukemia. This study concluded that atrial fibrillation is a common side effect associated with ibrutinib use in patients with chronic lymphocytic leukemia. Some background Chronic lymphocytic leukemia (CLL)...
Read MoreIn a nutshell This study aimed to investigate the outcomes and side effects of radical prostatectomy, external beam radiation therapy, and active surveillance in men with localized prostate cancer. This study concluded that radical prostatectomy led to a greater decrease in sexual function and urinary continence compared to the other two treatment...
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In a nutshell This study aimed to investigate the frequency and severity of the adverse events associated with non-hormonal drugs (NHD) used to treat hot flashes in breast cancer survivor patients. This study concluded that the use of high-dose NHD led to increased rates of adverse events when compared to patients not using NHD. Some...
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In a nutshell This trial examined whether altering the recommended dose of chemotherapy drugs during treatment was beneficial to patients. This trial concluded that altering doses of paclitaxel (Taxol) during chemotherapy could be beneficial to reduce neuropathy in patients with advanced non-small-cell lung cancer. Some...
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In a nutshell This study examined the effect of the patient’s health and number of medical conditions on the occurrence of side effects after transurethral resection of the prostate (TURP). Researchers concluded that these did not affect the occurrence of side effects after TURP. Most complications after TURP were considered mild. Some...
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