In a nutshell This study looked at giving 3 months or 12 months of dual antiplatelet medications following placement of a stent for patients with heart disease. It found that a shorter time on a dual regimen may lead to better outcomes than a longer period. Some background Coronary artery disease (CAD) occurs when the arteries leading to the...
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In a nutshell This study aimed to investigate the effect of tyrosine kinase inhibitor (TKI) dose reduction in patients with chronic myeloid leukemia (CML) after achieving a major molecular response (MMR). This study concluded that the TKI dose reduction was safe and effective for the majority of these...
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In a nutshell This trial is aiming to examine the safety and effectiveness of an experimental treatment called BPX-063, a CAR-T cell treatment, in patients with advanced HER-2 positive breast cancer. The main outcomes to be measured are the maximum tolerated dose of BPX-603 and the antitumor activity. This trial is being carried out across the...
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In a nutshell This trial is comparing conventional physical therapy, a powered exoskeleton (PE), and a combination of both treatments for stroke survivors. The main outcome will be the change in walking and balance before and after treatment. This trial will be conducted in California, US. The details A stroke happens when the blood flow to the brain...
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In a nutshell This trial is aiming to examine the safety and effectiveness of experimental treatment DF6002 alone or in combination with nivolumab (Opdivo) in the treatment of advanced solid tumors, including lung cancer. The main outcomes to be measured are drug toxicity and the response rate of patients to the drug. This trial is being carried out in...
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In a nutshell This trial is aiming to examine the safety and effectiveness of experimental treatment DF6002 alone or in combination with nivolumab (Opdivo) in the treatment of advanced solid tumors, including prostate cancer. The main outcomes to be measured are drug toxicity and the response rate of patients to the drug. This trial is being carried out...
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In a nutshell This trial is aiming to examine the safety and effectiveness of experimental treatment DF6002 alone or in combination with nivolumab (Opdivo) in the treatment of advanced solid tumors, including melanoma. The main outcomes to be measured are drug toxicity, and response rate of patients to the drug. This trial is being...
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In a nutshell This study aimed to compare the effectiveness of ibrutinib (Imbruvica) to idelalisib (Zydelig)–rituximab (Rituxan) combination for patients with chronic lymphocytic leukemia in a real-life setting. This study concluded that ibrutinib appears to improve survival...
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In a nutshell This study explored the outcomes of statin (cholesterol-lowering drugs) treatment in patients with prostate cancer (PCa) undergoing androgen deprivation therapy (ADT). The authors found that the combination of statins and ADT improved the outcomes of these patients and intermittent ADT (IADT) increased the time...
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In a nutshell This study looked at the effectiveness of a combination of bempedoic acid (Nexletol) and ezetimibe (Ezetrol) in lowering cholesterol. It found that this treatment combination significantly lowered cholesterol levels. Some background High cholesterol is a major risk factor for heart attack and stroke. Statins are the most commonly used...
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In a nutshell This study looked at the effectiveness of a combination of bempedoic acid (Nexletol) and ezetimibe (Ezetrol) in lowering cholesterol. It found that this treatment combination significantly lowered cholesterol levels. Some background High cholesterol is a major risk factor for heart attack and...
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In a nutshell This study looked at the long-term safety and effectiveness of 75mg vibegron (Gemtesa) for the treatment of overactive bladder (OAB). The authors found that vibegron demonstrated favorable long-term safety, tolerability, and effectiveness in patients with OAB. Some background OAB involves urinary symptoms such...
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