In a nutshell This article looked at the use of partial breast irradiation (PBI) versus whole-breast irradiation (WBI) as a treatment for breast cancer (BC). The authors found that PBI offered similar results when compared to WBI. Some background BC remains one of the most common forms of cancer found in women. Standard care for BC remains...
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In a nutshell This trial looked at the use of short-course radiotherapy (RT) followed by chemotherapy (CT) and delayed surgery to reduce distant metastases (tumor spread) in patients with locally advanced rectal cancer (LARC). The trial found that this treatment was more effective in controlling distant metastases when compared to standard...
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In a nutshell This study investigated the effectiveness of the probiotic combination Hexbio in the treatment of gut symptoms in patients with Parkinson’s disease (PD). Researchers suggested that these probiotics improved gut outcomes over 8 weeks of treatment. Some background PD is a chronic disease that affects the brain cells. The body...
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In a nutshell This study investigated the effectiveness and safety of combination regimens of brentuximab vedotin (BV; Adcetris), ipilimumab (Yervoy), and nivolumab (Opdivo) in patients with relapsed/refractory Hodgkin lymphoma (HL). The data showed that the treatment combinations had promising effectiveness and manageable side effects. Some background...
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In a nutshell This study investigated the safety and effectiveness of Aquablation using the AquaBeam system for the treatment of lower urinary tract symptoms (LUTS) as a result of benign prostatic hyperplasia (BPH). The results suggested that Aquablation using the AquaBeam system was safe and effective. Some background LUTS is a collection of symptoms...
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In a nutshell This study compared fertility medications for intrauterine insemination (IUI) for women with diminished ovarian reserve (DOR). It found that letrozole (Femara) and clomiphene citrate (Clomid) tablets gave similar results to injected gonadotropins (Gonal-F). Some background DOR is a condition in which few ovarian follicles (which...
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In a nutshell This study looked at the use of a temporarily implanted nitinol device (iTind) for the treatment of lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH). The authors found that iTind reduced LUTS and preserved sexual function in patients with BPH. Some background BPH is the non-cancerous...
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In a nutshell This trial looked at the length of adjuvant chemotherapy (AC; chemotherapy after surgery) for patients with stage III colon cancer. The authors found that 3 months of AC resulted in similar survival with reduced levels of toxicity, and cost compared to 6 months. Some background AC has been standard care for patients with...
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In a nutshell This study investigated the effectiveness and safety of focused ultrasound subthalamotomy (FUS) in patients with Parkinson’s disease (PD). Researchers suggested that FUS improved symptoms of PD. Some background PD is a chronic disorder that affects the brain cells. These cells lose their ability to control body functions,...
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In a nutshell This study investigated whether lenalidomide maintenance therapy after intensive chemoimmunotherapy and first-line autologous hematopoietic stem-cell transplantation (AHSCT) improved the outcomes of patients with mantle cell lymphoma (MCL). The data showed that lenalidomide maintenance after AHSCT improved the survival without...
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In a nutshell The authors compared the BEAM (BCNU, etoposide, cytarabine, and melphalan) and MITO/MEL (mitoxantrone, melphalan) regimens before autologous stem cell transplantation (ASCT) in patients with Hodgkin lymphoma (HL). The study found that both regimens were similarly effective with fewer lung side effects with MITO/MEL. Some...
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Barry Nelson, Patient Advisor at Brigham and Women’s Hospital Center for Patients and Families participated in a webinar on January 11 organized by The Center for Health Education Research Service in Boston, Massachusetts. [1] During the webinar, Nelson described his experience as a cancer survivor. “I was diagnosed with advanced lung cancer...
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